Table 4 Definition of molecular response... | American Society of Hematology

Table 4

Definition of molecular response in ET and PV

Response grade	Definition
Complete response	Reduction of any specific molecular abnormality to undetectable levels
Partial response*	(1) A reduction of ≥ 50% from baseline value in patients with < 50% mutant allele burden at baseline OR (2) reduction of ≥ 25% from baseline value in patients with > 50% mutant allele burden at baseline.
No response	Any response that does not satisfy partial response

Response grade	Definition
Complete response	Reduction of any specific molecular abnormality to undetectable levels
Partial response*	(1) A reduction of ≥ 50% from baseline value in patients with < 50% mutant allele burden at baseline OR (2) reduction of ≥ 25% from baseline value in patients with > 50% mutant allele burden at baseline.
No response	Any response that does not satisfy partial response

Applies only to patients with a baseline value of mutant allele burden greater than 10%.