Table 1 Tracking of tumor-derived Ig V... | American Society of Hematology

Table 1

Tracking of tumor-derived Ig V-genes in the blood and BM of patients with PCNSL

Case no./chain	Location	Tumor clone identified*	No. of tumor-derived sequences
10/V_L	Biopsy	+	25
	Blood	+	20 (clone 1), 5 (clone 2)
	BM	+	9 (clone 1), 21 (clone 2)
10/V_H	Biopsy	+	NA
	Blood	−	−
	BM	−	−
11/V_L	Biopsy	+	25
	Blood	+	25
	BM	+	25
11/V_H	Biopsy	+	23
	Blood	−	−
	BM	+†	24
12/V_L	Biopsy	+	25
	Blood	+	25
	BM	−	−
12/V_H	Biopsy	+	25
	Blood	+	25
	BM	−	−

Case no./chain	Location	Tumor clone identified*	No. of tumor-derived sequences
10/V_L	Biopsy	+	25
	Blood	+	20 (clone 1), 5 (clone 2)
	BM	+	9 (clone 1), 21 (clone 2)
10/V_H	Biopsy	+	NA
	Blood	−	−
	BM	−	−
11/V_L	Biopsy	+	25
	Blood	+	25
	BM	+	25
11/V_H	Biopsy	+	23
	Blood	−	−
	BM	+†	24
12/V_L	Biopsy	+	25
	Blood	+	25
	BM	−	−
12/V_H	Biopsy	+	25
	Blood	+	25
	BM	−	−

NA indicates not assessed.

Tumor-derived sequence (FR1-CDR3) identified by CDR3-specific PCR.

Tumor-derived sequence (CDR2-FR4) identified by CDR2-specific PCR.