Acute GVHD
| UPN . | Day . | Organ . | Grade* . | Treatment . | |||
|---|---|---|---|---|---|---|---|
| Primary . | Response . | Secondary . | Response . | ||||
| 003 | +64 | GI | B | Corticosteroids | Complete | — | — |
| 005 | +20 | GI | C | Corticosteroids | Complete | — | — |
| 011 | +49 | GI | B | Corticosteroids | Complete | — | — |
| 015 | +27 | Skin, liver | C | Corticosteroids | Partial | Dacluzimab, MMF | Complete |
| 016 | +39 | Skin | B | Corticosteroids | Complete | — | — |
| 017 | +38 | GI† | B | N/A | N/A | — | — |
| 018 | +22 | GI, liver | D | Corticosteroids | Partial | Sirolimus, tacrolimus | Died‡ |
| 020 | +25 | GI | C | Corticosteroids | Complete | — | — |
| 024 | +38 | GI | C | Corticosteroids | Complete | — | — |
| UPN . | Day . | Organ . | Grade* . | Treatment . | |||
|---|---|---|---|---|---|---|---|
| Primary . | Response . | Secondary . | Response . | ||||
| 003 | +64 | GI | B | Corticosteroids | Complete | — | — |
| 005 | +20 | GI | C | Corticosteroids | Complete | — | — |
| 011 | +49 | GI | B | Corticosteroids | Complete | — | — |
| 015 | +27 | Skin, liver | C | Corticosteroids | Partial | Dacluzimab, MMF | Complete |
| 016 | +39 | Skin | B | Corticosteroids | Complete | — | — |
| 017 | +38 | GI† | B | N/A | N/A | — | — |
| 018 | +22 | GI, liver | D | Corticosteroids | Partial | Sirolimus, tacrolimus | Died‡ |
| 020 | +25 | GI | C | Corticosteroids | Complete | — | — |
| 024 | +38 | GI | C | Corticosteroids | Complete | — | — |
GI indicates gastrointestinal; MMF, mycophenolate mofetil; and —, not applicable. Other abbreviations as in Table 1.
IBMTR grading criteria.
Diagnosed on histologic appearance of GI biopsies postmortem.
UPN018 died of probable fungal infection (radiologic evidence) while on immunosuppression for aGVHD.