Peptide 12 promotes in vivo angiogenesis in a dose-dependent manner
| . | 10 μg/pellet . | 100 μg/pellet . |
|---|---|---|
| Peptide 12 | 2.0 ± 0.5* | 8.2 ± 2.0* |
| Peptide 12 Y220A | 0.3 ± 0.3 | 1.4 ± 0.8 |
| . | 10 μg/pellet . | 100 μg/pellet . |
|---|---|---|
| Peptide 12 | 2.0 ± 0.5* | 8.2 ± 2.0* |
| Peptide 12 Y220A | 0.3 ± 0.3 | 1.4 ± 0.8 |
The effect of 10 and 100 μg/pellet of peptide 12 or Y220A peptide was tested in the rabbit cornea assay. Data (mean ± SEM) are reported as angiogenic score at day 17 and are the means of 6 implants for each experimental point. (One-way analysis of variance P < .001.)
P < .05 peptide 12 versus Y220A peptide (Student-Newman-Keuls multiple comparison test).