Table 1 Comparison of Mll genotypes... | American Society of Hematology

Table 1

Comparison of Mll genotypes

Characteristic	Mll^PTD/WT	Mll^PTD/−	Mll^WT/−	Mll^WT/WT
Premature death	no	yes*	no	no
HoxA expression	increased	increased	decreased but NS	normal
Increased H3 (Lys4)	yes	yes	no	no
Increased BFU-E	yes	yes	no	—
Increased CFU-GEMM	yes	no	no	—
Increased CFU-GM	yes	yes	no	—

Characteristic	Mll^PTD/WT	Mll^PTD/−	Mll^WT/−	Mll^WT/WT
Premature death	no	yes*	no	no
HoxA expression	increased	increased	decreased but NS	normal
Increased H3 (Lys4)	yes	yes	no	no
Increased BFU-E	yes	yes	no	—
Increased CFU-GEMM	yes	no	no	—
Increased CFU-GM	yes	yes	no	—

NS indicates not significant; BFU-E, erythroid progenitors; and —, not applicable.

Pups died by postpartum day 1.