EZH2 target gene enrichment in miR-26a-induced gene expression pattern
| Gene symbol . | Description . | Probe set . | Geometric mean of intensities (class empty/class miR-26a) . | Fold change after PcG knock-down* . |
|---|---|---|---|---|
| ARHGAP24 | Rho GTPase-activating protein 24 | 1566825_at | 0.7037292 | 1.5 |
| ATAD2 | ATPase family, AAA domain containing 2 | 222740_at | 1.3870516 | −1.9 |
| CCNB1 | Cyclin B1 | 214710_s_at | 1.3400383 | −1.5 |
| CCNE2 | Cyclin E2 | 205034_at | 1.5680341 | −2.5 |
| CDC25A | Cell division cycle 25 homolog A (S. cerevisiae) | 1555772_a_at | 1.3642922 | −1.9 |
| CDC6 | Cell division cycle 6 homolog (S. cerevisiae) | 203968_s_at | 1.4108894 | −3.1 |
| CDT1 | Chromatin licensing and DNA replication factor 1 | 228868_x_at | 1.5277866 | −2.2 |
| CHAF1A | Chromatin assembly factor 1, subunit A (p150) | 203976_s_at | 1.5635639 | −6.2 |
| CUGBP2 | CUG triplet repeat, RNA binding protein 2 | 242268_at | 0.7193129 | 1.7 |
| DCC1 | defective in sister chromatid cohesion homolog 1 (S. cerevisiae) | 219000_s_at | 1.3318879 | −1.6 |
| GMNN | Geminin, DNA replication inhibitor | 218350_s_at | 1.3320183 | −2 |
| GTSE1 | G2- and S-phase expressed 1 | 215942_s_at | 1.4042593 | −3.4 |
| HELLS | Helicase, lymphoid-specific | 220085_at | 1.3691602 | −2.3 |
| LRAP | Leukocyte-derived arginine aminopeptidase | 240338_at | 0.630956 | 1.4 |
| MCM10 | MCM10 minichromosome maintenance deficient 10 (S. cerevisiae) | 220651_s_at | 1.4244193 | −3.1 |
| MCM4 | MCM4 minichromosome maintenance deficient 4 (S. cerevisiae) | 222037_at | 1.2871303 | −4.8 |
| MKI67 | Antigen identified by monoclonal antibody Ki-67 | 212022_s_at | 1.4520355 | −2.7 |
| MYBL1 | v-myb myeloblastosis viral oncogene homolog (avian)-like 1 | 213906_at | 1.5254951 | −1.7 |
| ORC1L | Origin recognition complex, subunit 1-like (yeast) | 205085_at | 1.511178 | −2.9 |
| PDE4DIP | Phosphodiesterase 4D interacting protein (myomegalin) | 232615_at | 0.7658641 | 1.1 |
| RFC4 | Replication factor C (activator 1) 4, 37kDa | 204023_at | 1.4484428 | −1.9 |
| SKP2 | S-phase kinase-associated protein 2 (p45) | 210567_s_at | 1.4732182 | −2.2 |
| SLC17A5 | Solute carrier family 17 (anion/sugar transporter), member 5 | 221041_s_at | 0.7774443 | 1.3 |
| SOX5 | SRY (sex determining region Y)-box 5 | 215768_at | 0.685878 | 1.7 |
| TncRNA | Trophoblast-derived noncoding RNA | 238320_at | 0.5457627 | 1.9 |
| ZBTB1 | Zinc finger and BTB domain containing 1 | 1557036_at | 0.7410104 | 4.9 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 222863_at | 0.7321463 | 2.6 |
| Gene symbol . | Description . | Probe set . | Geometric mean of intensities (class empty/class miR-26a) . | Fold change after PcG knock-down* . |
|---|---|---|---|---|
| ARHGAP24 | Rho GTPase-activating protein 24 | 1566825_at | 0.7037292 | 1.5 |
| ATAD2 | ATPase family, AAA domain containing 2 | 222740_at | 1.3870516 | −1.9 |
| CCNB1 | Cyclin B1 | 214710_s_at | 1.3400383 | −1.5 |
| CCNE2 | Cyclin E2 | 205034_at | 1.5680341 | −2.5 |
| CDC25A | Cell division cycle 25 homolog A (S. cerevisiae) | 1555772_a_at | 1.3642922 | −1.9 |
| CDC6 | Cell division cycle 6 homolog (S. cerevisiae) | 203968_s_at | 1.4108894 | −3.1 |
| CDT1 | Chromatin licensing and DNA replication factor 1 | 228868_x_at | 1.5277866 | −2.2 |
| CHAF1A | Chromatin assembly factor 1, subunit A (p150) | 203976_s_at | 1.5635639 | −6.2 |
| CUGBP2 | CUG triplet repeat, RNA binding protein 2 | 242268_at | 0.7193129 | 1.7 |
| DCC1 | defective in sister chromatid cohesion homolog 1 (S. cerevisiae) | 219000_s_at | 1.3318879 | −1.6 |
| GMNN | Geminin, DNA replication inhibitor | 218350_s_at | 1.3320183 | −2 |
| GTSE1 | G2- and S-phase expressed 1 | 215942_s_at | 1.4042593 | −3.4 |
| HELLS | Helicase, lymphoid-specific | 220085_at | 1.3691602 | −2.3 |
| LRAP | Leukocyte-derived arginine aminopeptidase | 240338_at | 0.630956 | 1.4 |
| MCM10 | MCM10 minichromosome maintenance deficient 10 (S. cerevisiae) | 220651_s_at | 1.4244193 | −3.1 |
| MCM4 | MCM4 minichromosome maintenance deficient 4 (S. cerevisiae) | 222037_at | 1.2871303 | −4.8 |
| MKI67 | Antigen identified by monoclonal antibody Ki-67 | 212022_s_at | 1.4520355 | −2.7 |
| MYBL1 | v-myb myeloblastosis viral oncogene homolog (avian)-like 1 | 213906_at | 1.5254951 | −1.7 |
| ORC1L | Origin recognition complex, subunit 1-like (yeast) | 205085_at | 1.511178 | −2.9 |
| PDE4DIP | Phosphodiesterase 4D interacting protein (myomegalin) | 232615_at | 0.7658641 | 1.1 |
| RFC4 | Replication factor C (activator 1) 4, 37kDa | 204023_at | 1.4484428 | −1.9 |
| SKP2 | S-phase kinase-associated protein 2 (p45) | 210567_s_at | 1.4732182 | −2.2 |
| SLC17A5 | Solute carrier family 17 (anion/sugar transporter), member 5 | 221041_s_at | 0.7774443 | 1.3 |
| SOX5 | SRY (sex determining region Y)-box 5 | 215768_at | 0.685878 | 1.7 |
| TncRNA | Trophoblast-derived noncoding RNA | 238320_at | 0.5457627 | 1.9 |
| ZBTB1 | Zinc finger and BTB domain containing 1 | 1557036_at | 0.7410104 | 4.9 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 222863_at | 0.7321463 | 2.6 |
Bracken et al.34