Kinetic parameters of VWF:Ag
| Parameter . | Non-O (n = 19) . | O (n = 28) . | P . | ||||
|---|---|---|---|---|---|---|---|
| Mean . | SE . | Range . | Mean . | SE . | Range . | ||
| A (U/dL) | 133.8 | 10.8 | 71-229 | 116.6 | 7.2 | 46-216 | NS |
| Kel (h-1) | 0.041 | 0.005 | 0.008-0.098 | 0.083 | 0.006 | 0.036-0.146 | <.0001 |
| Kre (h-1) | 4.88 | 0.48 | 2.09-9.39 | 4.15 | 0.38 | 0.87-7.90 | NS |
| AUC (U/dL×h) | 5091 | 1449 | 1360-28907 | 1541 | 145 | 558-3764 | .025 |
| tel (h) | 25.5 | 5.3 | 7.1-87.7 | 10.0 | 0.8 | 4.7-19.4 | .009 |
| tre (h) | 0.17 | 0.02 | 0.07-0.33 | 0.23 | 0.03 | 0.09-0.80 | NS |
| to(h) | 0.34 | 0.04 | 0-0.73 | 0.33 | 0.028 | 0-0.64 | NS |
| B (U/dL) | 114.2 | 8.6 | 53.7-199.0 | 79.2 | 5.8 | 46.5-122.0 | .001 |
| r2 | 0.905 | 0.025 | 0.64-0.99 | 0.954 | 0.009 | 0.79-0.99 | — |
| Parameter . | Non-O (n = 19) . | O (n = 28) . | P . | ||||
|---|---|---|---|---|---|---|---|
| Mean . | SE . | Range . | Mean . | SE . | Range . | ||
| A (U/dL) | 133.8 | 10.8 | 71-229 | 116.6 | 7.2 | 46-216 | NS |
| Kel (h-1) | 0.041 | 0.005 | 0.008-0.098 | 0.083 | 0.006 | 0.036-0.146 | <.0001 |
| Kre (h-1) | 4.88 | 0.48 | 2.09-9.39 | 4.15 | 0.38 | 0.87-7.90 | NS |
| AUC (U/dL×h) | 5091 | 1449 | 1360-28907 | 1541 | 145 | 558-3764 | .025 |
| tel (h) | 25.5 | 5.3 | 7.1-87.7 | 10.0 | 0.8 | 4.7-19.4 | .009 |
| tre (h) | 0.17 | 0.02 | 0.07-0.33 | 0.23 | 0.03 | 0.09-0.80 | NS |
| to(h) | 0.34 | 0.04 | 0-0.73 | 0.33 | 0.028 | 0-0.64 | NS |
| B (U/dL) | 114.2 | 8.6 | 53.7-199.0 | 79.2 | 5.8 | 46.5-122.0 | .001 |
| r2 | 0.905 | 0.025 | 0.64-0.99 | 0.954 | 0.009 | 0.79-0.99 | — |
NS indicates not significant; and —, not applicable.