Stat5−/− embryos mice display severe microcytosis
| E16.5 embryos . | Wild-type . | Stat5−/− . |
|---|---|---|
| RBC, 106/mm3 | 2.4 ± 0.4 | 1.0 ± 0.3** |
| Hct, % | 31.4 ± 1.8 | 9.8 ± 0.7** |
| Hgb, g/L | 91 ± 12 | 23 ± 7** |
| MCV, μm3 | 128.2 ± 3.7 | 95.9 ± 5.2** |
| MCH, pg | 37.5 ± 0.3 | 23.1 ± 0.7** |
| E16.5 embryos . | Wild-type . | Stat5−/− . |
|---|---|---|
| RBC, 106/mm3 | 2.4 ± 0.4 | 1.0 ± 0.3** |
| Hct, % | 31.4 ± 1.8 | 9.8 ± 0.7** |
| Hgb, g/L | 91 ± 12 | 23 ± 7** |
| MCV, μm3 | 128.2 ± 3.7 | 95.9 ± 5.2** |
| MCH, pg | 37.5 ± 0.3 | 23.1 ± 0.7** |
Blood indices of E16.5 Stat5−/− embryos. Data are presented as mean ± SEM; n = 15 each genotype.
RBC indicates red blood cell count; Hct, hematocrit; Hgb, hemoglobin content; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin.
*P < .05; **P < .01.