Transcription binding sites containing promoter polymorphisms: loss or gain of the transcription factor binding sites relative to the alleles of haplotype *1
| Haplotype . | SNPs . | Loss . | Gain . | ||||
|---|---|---|---|---|---|---|---|
| −1610 . | −1574 . | −1349 . | −1338 . | −216 . | |||
| *1 | C | A | G | C | T | None | None |
| *4 | T | A | G | C | C | None | Octamer-binding factor 1, POU-specific domain |
| *4 | — | — | — | — | C | Neural retinal basic leucine zipper factor (bZIP) | None |
| *4 | — | — | — | — | C | c-Ets-2 binding site | None |
| *5 | G | G | C | T | T | Thing1/E47 heterodimer, TH1 bHLH member | None |
| *5 | — | — | C | — | — | CCAAT/enhancer binding protein beta | None |
| *5 | — | — | C | — | — | Octamer binding site (OCT1/OCT2) | None |
| *5 | — | — | — | T | — | None | Promyelocytic leukemia zinc finger |
| Haplotype . | SNPs . | Loss . | Gain . | ||||
|---|---|---|---|---|---|---|---|
| −1610 . | −1574 . | −1349 . | −1338 . | −216 . | |||
| *1 | C | A | G | C | T | None | None |
| *4 | T | A | G | C | C | None | Octamer-binding factor 1, POU-specific domain |
| *4 | — | — | — | — | C | Neural retinal basic leucine zipper factor (bZIP) | None |
| *4 | — | — | — | — | C | c-Ets-2 binding site | None |
| *5 | G | G | C | T | T | Thing1/E47 heterodimer, TH1 bHLH member | None |
| *5 | — | — | C | — | — | CCAAT/enhancer binding protein beta | None |
| *5 | — | — | C | — | — | Octamer binding site (OCT1/OCT2) | None |
| *5 | — | — | — | T | — | None | Promyelocytic leukemia zinc finger |
All SNPs in the promoter region (tagSNPs and those in linkage disequilibrium with tagSNPS) are analyzed by MatInspector. Only polymorphisms positioned within the binding sites (affected by SNPs) for transcription factors that are expressed in lymphocytes are listed.
Boldface indicates gain; underlining, loss; and —, as above.