Categories of TP53-associated genes in MM cell lines and newly diagnosis primary tumors*
| Apoptosis . | Cell cycle . | DNA repair/chromatin modifier . | Cell growth differentiation . | Signal transduction . | Biosynthesis metabolism . | Posttranslational modification . | Transcription regulation . | Transport and ion channel . | Unknown . |
|---|---|---|---|---|---|---|---|---|---|
| TP53 | APP | IFIT5 | FXYD5 | ARHGAP25 | STT3B | SAT2 | ZNF600 | LAPTM4B | CYB5D2 |
| TRIM13 | ABCB9 | ANKRA2 | MCC | RTN2 | ECHDC2 | SLAMF7 | L3MBTL4* | OSBPL10 | UNC93B1 |
| NADSYN1 | GAA | PHLDB1 | MKNK2 | WNT16 | ENPP4* | MAN1C1 | KCNS3 | SIDT1 | |
| TRIM22† | CEP55* | TUBA1A* | KLHL24 | DEPDC1* | INTS7* | THEX1* | TMEM57 | ||
| AGRN | BRCA1* | CDCA7* | DLC1 | HIGD2A | |||||
| CENTD2 | ANLN* | CDCA2* | OPN3* | FKSG44 | |||||
| SESN1 | PYGL* | HFE* | B3GALNT1* | C14orf28 | |||||
| TM7SF2 | CCNE2* | RIF1* | SPRED1* | LOC387763 | |||||
| NCKAP1 | ASPM* | NEIL3* | TncRNA | ||||||
| COPG | SUV39H2* | SLC4A7* | C18orf1 | ||||||
| STAT3 | CDC25A* | DCUN1D4* | |||||||
| ALOX5 | SEPP1* | FANCI* | |||||||
| ZMAT3† | RIT1* | CD302* | |||||||
| NOTCH1† | KIF2C* | C5orf34* | |||||||
| BTG2 | S100A4* | FAM111B* | |||||||
| RAB1A | MEIS1* | C18orf54* | |||||||
| TNFRSF10B† | SGOL2* | ||||||||
| HDLBP |
| Apoptosis . | Cell cycle . | DNA repair/chromatin modifier . | Cell growth differentiation . | Signal transduction . | Biosynthesis metabolism . | Posttranslational modification . | Transcription regulation . | Transport and ion channel . | Unknown . |
|---|---|---|---|---|---|---|---|---|---|
| TP53 | APP | IFIT5 | FXYD5 | ARHGAP25 | STT3B | SAT2 | ZNF600 | LAPTM4B | CYB5D2 |
| TRIM13 | ABCB9 | ANKRA2 | MCC | RTN2 | ECHDC2 | SLAMF7 | L3MBTL4* | OSBPL10 | UNC93B1 |
| NADSYN1 | GAA | PHLDB1 | MKNK2 | WNT16 | ENPP4* | MAN1C1 | KCNS3 | SIDT1 | |
| TRIM22† | CEP55* | TUBA1A* | KLHL24 | DEPDC1* | INTS7* | THEX1* | TMEM57 | ||
| AGRN | BRCA1* | CDCA7* | DLC1 | HIGD2A | |||||
| CENTD2 | ANLN* | CDCA2* | OPN3* | FKSG44 | |||||
| SESN1 | PYGL* | HFE* | B3GALNT1* | C14orf28 | |||||
| TM7SF2 | CCNE2* | RIF1* | SPRED1* | LOC387763 | |||||
| NCKAP1 | ASPM* | NEIL3* | TncRNA | ||||||
| COPG | SUV39H2* | SLC4A7* | C18orf1 | ||||||
| STAT3 | CDC25A* | DCUN1D4* | |||||||
| ALOX5 | SEPP1* | FANCI* | |||||||
| ZMAT3† | RIT1* | CD302* | |||||||
| NOTCH1† | KIF2C* | C5orf34* | |||||||
| BTG2 | S100A4* | FAM111B* | |||||||
| RAB1A | MEIS1* | C18orf54* | |||||||
| TNFRSF10B† | SGOL2* | ||||||||
| HDLBP |