Patient characteristics
Characteristic . | No. (%) . |
---|---|
Patient | |
Sex | |
Male | 70 (67) |
Female | 35 (33) |
Diagnostic category | |
Severe combined immunodeficiency (SCID) | 43 (41) |
ADA-deficient SCID | 13 (12) |
Combined immunodeficiency, undefined | 19 (18) |
Wiskott-Aldrich syndrome | 10 (10) |
Chédiak-Higashi syndrome | 3 (3) |
CGD | 2 (2) |
CD40 ligand | 4 (4) |
Intractable colitis and immunodeficiency | 2 (2) |
γ-Interferon deficiency | 1 (1) |
XLP/HLH | 2 (2) |
LAD type 1 | 2 (2) |
Undefined neutrophil defect | 3 (3) |
XLT | 1 (1) |
Donor | |
Matched sibling donor (MSD) | 35 (33) |
Matched family donor (MFD) | 8 (8) |
Mismatched family donor (MMFD) | 1 (1) |
Matched unrelated donor (MUD) | 31 (30) |
Mismatched unrelated donor (MMUD) | 10 (10) |
Haploidentical donor (HAPLO) | 20 (19) |
Conditioning | |
Full | 44 (42) |
Reduced intensity | 36 (35) |
None | 23 (23) |
Ethnic background | |
White British | 61 (58) |
White Irish | 5 (5) |
Asian | 26 (25) |
European | 8 (8) |
Other | 5 (5) |
Characteristic . | No. (%) . |
---|---|
Patient | |
Sex | |
Male | 70 (67) |
Female | 35 (33) |
Diagnostic category | |
Severe combined immunodeficiency (SCID) | 43 (41) |
ADA-deficient SCID | 13 (12) |
Combined immunodeficiency, undefined | 19 (18) |
Wiskott-Aldrich syndrome | 10 (10) |
Chédiak-Higashi syndrome | 3 (3) |
CGD | 2 (2) |
CD40 ligand | 4 (4) |
Intractable colitis and immunodeficiency | 2 (2) |
γ-Interferon deficiency | 1 (1) |
XLP/HLH | 2 (2) |
LAD type 1 | 2 (2) |
Undefined neutrophil defect | 3 (3) |
XLT | 1 (1) |
Donor | |
Matched sibling donor (MSD) | 35 (33) |
Matched family donor (MFD) | 8 (8) |
Mismatched family donor (MMFD) | 1 (1) |
Matched unrelated donor (MUD) | 31 (30) |
Mismatched unrelated donor (MMUD) | 10 (10) |
Haploidentical donor (HAPLO) | 20 (19) |
Conditioning | |
Full | 44 (42) |
Reduced intensity | 36 (35) |
None | 23 (23) |
Ethnic background | |
White British | 61 (58) |
White Irish | 5 (5) |
Asian | 26 (25) |
European | 8 (8) |
Other | 5 (5) |
CGD indicates chronic granulomatous disease; XLP, X-linked lymphoproliferative disease; HLH, hemophagocytic lymphohistiocytosis; LAD, leucocyte adhesion deficiency; and XLT, X-linked thrombocytopenia.