Table 3

Multivariable repeated measures analysis of complete blood counts by status, HTLV-I versus seronegative

OutcomeHTLV-IVisitAgeFemaleRaceAlcoholSmoking
Hemoglobin NS +1 — −15 −7* — — 
MCV NS +0.4 +0.1 −1.2 −3.0*, −1.2 +2.2 — 
Platelets +16 544 6749 NS +37 731 +17 473 NS NS 
Total WBC NS NS −19 +575 −532* −529 +1248§ 
Lymphocytes NS −67 −9 +149 +163* −272 +406§ 
Neutrophils NS NS −9 +416 −601* −220 +697§ 
Monocytes NS +19 — — −30* −33 +72§ 
Eosinophils NS +3 — — −31* NS +26§ 
Basophils NS −2 NS +5 NS NS +20§ 
OutcomeHTLV-IVisitAgeFemaleRaceAlcoholSmoking
Hemoglobin NS +1 — −15 −7* — — 
MCV NS +0.4 +0.1 −1.2 −3.0*, −1.2 +2.2 — 
Platelets +16 544 6749 NS +37 731 +17 473 NS NS 
Total WBC NS NS −19 +575 −532* −529 +1248§ 
Lymphocytes NS −67 −9 +149 +163* −272 +406§ 
Neutrophils NS NS −9 +416 −601* −220 +697§ 
Monocytes NS +19 — — −30* −33 +72§ 
Eosinophils NS +3 — — −31* NS +26§ 
Basophils NS −2 NS +5 NS NS +20§ 

Numbers represent effect size of each predictor's significant (P < .05 or stronger) association with the outcome, in the following units: hemoglobin, g/L; MCV, fL; cell counts, cells/μL. Unless otherwise indicated, visit is per incremental 2-year follow-up period. Age is in years; alcohol intake is categorized as 0 to 1 drinks per week, 2 to 7 drinks per week, and more than 7 drinks per week versus none; smoking is categorized as 0 pack-years, more than 0 to 15 pack-years, more than 15 pack-years; education is dichotomized at high school graduate or less; annual baseline income is dichotomized at $30 000; injection drug use is ever versus never. Coefficients for blood center, education, income, injection drug use, donation type, and interaction terms between HTLV infection status and time are not shown.

NS indicates a predictor remained in the model but was not significant; — indicates the predictor was dropped from the final model.

*

Black race.

Hispanic or other race.

More than 7 drinks per week versus none.

§

More than 15 pack-years versus none. Complete model outputs are available in Table S1.

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