Clinical and phenotypic data in 47 cases of pDC neoplasms
Case no. . | Age, y/sex . | Site of involvement . | CD4 . | CD45RA . | CD43 . | CD56 . | CD123 . | TCL1 . | TdT . | |
---|---|---|---|---|---|---|---|---|---|---|
CD4+CD56+ hematodermic neoplasm | ||||||||||
1 | 77/F | Skin | + | + | + | + | Scat'rd+ | nd | Scat'rd+ | |
2 | 73/F | Skin | + | nd | nd | − | nd | nd | + | |
3 | 61/M | Skin and bone marrow | + | + | + | + (30%) | + | + | − | |
4 | 67/M | Skin | + | nd | + | + | + | + | − | |
5 | 60/M | Skin | + | + | + | + | + | + | + | |
6 | 80/M | Bone marrow | + | + | + | + | + | + | – | |
7 | 51/M | Bone marrow | + | + | + | + | + | nd | – | |
8 | 75/M | Skin | + | + | + | + | – | + | – | |
9 | 78/F | Spleen | + | + | + | + | + | + | – | |
10 | 80/M | Skin | + | + | + | – | + | + | – | |
11 | 78/M | Bone marrow | + | + | + | + | + | + | – | |
12 | 45/F | na | + | + | + | + | + | + | – | |
13 | 58/M | Bone marrow | + | + | + | + | + | + | – | |
14 | 71/M | Skin | + | + | + | + | + | + | + | |
15 | 72/M | Skin | + | + | + | + | + | nd | – | |
16 | 30/M | Skin | + | + | + | +/− | + | + | −/+ | |
17 | na | na | + | + | + | +/− | + | + | +/− | |
18 | 31/M | Skin | + | + | + | + | + | + | −/+ | |
19 | 57 M | Skin, lymph node, and bone marrow | + | nd | + | + | nd | nd | + | |
20 | 68 F | Skin | + | nd | + | + | nd | nd | + | |
21 | 12 F | Skin | + | nd | + | + | nd | nd | + | |
22 | 25/F | Skin | + | nd | + | + | + | + | nd | |
23 | 77/M | Skin | + | + | + | + | + | + | − | |
24 | 35/F | Skin | + | nd | + | + | + | + | − | |
25 | 80/M | Skin | + | nd | nd | + | nd | nd | nd | |
26 | 96/F | Skin | + | nd | + | + | + | + | + (30%) | |
27 | 73/M | Skin | + | nd | + | + | + | + | − | |
28 | 76/M | Skin | + | nd | + | + | + | + | + (50%) | |
29 | 54/F | Skin | + | nd | − | + | + | + | + (80%) | |
30 | 71/M | Skin | + | nd | + | + | + | + | − | |
31 | 63/M | Skin | + | nd | nd | + | + | + | + (10%) | |
32 | 8/M | Skin | + | + | + | + | + | + | − | |
33 | 64/M | Lymph node | + | nd | + | + | nd | + | + | |
34 | 84/M | Skin | + | + | + | + | + | + | − | |
35 | 60/F | Skin | + | nd | nd | + | nd | nd | nd | |
36 | 83/M | Skin | + | nd | nd | + | + | + | − | |
37 | 75/M | Skin | + | nd | + | + | + | + | − | |
38 | 25/M | Skin | + | nd | nd | + | + | + | − | |
39 | 70/F | Skin | + | nd | + | + | nd | + | − | |
40 | 88/F | Skin | + | + | + | + | + | + | + (10%) | |
41 | 72/M | Skin | + | + | + | + | + | + | − | |
pDC proliferations associated with a myeloproliferative disorder | ||||||||||
42 | 52/M | Lymph node | + | + | + | (+) | + | + | − | |
43 | 63/F | Lymph node | + | + | + | (+) | + | (+) | − | |
44 | 24/M | Lymph node and skin | + | + | + | − | + | (+) | − | |
45 | 62/F | Lymph node | + | + | + | − | + | (+) | − | |
46 | 65/M | Lymph node | + | nd | + | (+) | + | + | − | |
47 | 71/M | Bone marrow | + | + | + | − | + | nd | − |
Case no. . | Age, y/sex . | Site of involvement . | CD4 . | CD45RA . | CD43 . | CD56 . | CD123 . | TCL1 . | TdT . | |
---|---|---|---|---|---|---|---|---|---|---|
CD4+CD56+ hematodermic neoplasm | ||||||||||
1 | 77/F | Skin | + | + | + | + | Scat'rd+ | nd | Scat'rd+ | |
2 | 73/F | Skin | + | nd | nd | − | nd | nd | + | |
3 | 61/M | Skin and bone marrow | + | + | + | + (30%) | + | + | − | |
4 | 67/M | Skin | + | nd | + | + | + | + | − | |
5 | 60/M | Skin | + | + | + | + | + | + | + | |
6 | 80/M | Bone marrow | + | + | + | + | + | + | – | |
7 | 51/M | Bone marrow | + | + | + | + | + | nd | – | |
8 | 75/M | Skin | + | + | + | + | – | + | – | |
9 | 78/F | Spleen | + | + | + | + | + | + | – | |
10 | 80/M | Skin | + | + | + | – | + | + | – | |
11 | 78/M | Bone marrow | + | + | + | + | + | + | – | |
12 | 45/F | na | + | + | + | + | + | + | – | |
13 | 58/M | Bone marrow | + | + | + | + | + | + | – | |
14 | 71/M | Skin | + | + | + | + | + | + | + | |
15 | 72/M | Skin | + | + | + | + | + | nd | – | |
16 | 30/M | Skin | + | + | + | +/− | + | + | −/+ | |
17 | na | na | + | + | + | +/− | + | + | +/− | |
18 | 31/M | Skin | + | + | + | + | + | + | −/+ | |
19 | 57 M | Skin, lymph node, and bone marrow | + | nd | + | + | nd | nd | + | |
20 | 68 F | Skin | + | nd | + | + | nd | nd | + | |
21 | 12 F | Skin | + | nd | + | + | nd | nd | + | |
22 | 25/F | Skin | + | nd | + | + | + | + | nd | |
23 | 77/M | Skin | + | + | + | + | + | + | − | |
24 | 35/F | Skin | + | nd | + | + | + | + | − | |
25 | 80/M | Skin | + | nd | nd | + | nd | nd | nd | |
26 | 96/F | Skin | + | nd | + | + | + | + | + (30%) | |
27 | 73/M | Skin | + | nd | + | + | + | + | − | |
28 | 76/M | Skin | + | nd | + | + | + | + | + (50%) | |
29 | 54/F | Skin | + | nd | − | + | + | + | + (80%) | |
30 | 71/M | Skin | + | nd | + | + | + | + | − | |
31 | 63/M | Skin | + | nd | nd | + | + | + | + (10%) | |
32 | 8/M | Skin | + | + | + | + | + | + | − | |
33 | 64/M | Lymph node | + | nd | + | + | nd | + | + | |
34 | 84/M | Skin | + | + | + | + | + | + | − | |
35 | 60/F | Skin | + | nd | nd | + | nd | nd | nd | |
36 | 83/M | Skin | + | nd | nd | + | + | + | − | |
37 | 75/M | Skin | + | nd | + | + | + | + | − | |
38 | 25/M | Skin | + | nd | nd | + | + | + | − | |
39 | 70/F | Skin | + | nd | + | + | nd | + | − | |
40 | 88/F | Skin | + | + | + | + | + | + | + (10%) | |
41 | 72/M | Skin | + | + | + | + | + | + | − | |
pDC proliferations associated with a myeloproliferative disorder | ||||||||||
42 | 52/M | Lymph node | + | + | + | (+) | + | + | − | |
43 | 63/F | Lymph node | + | + | + | (+) | + | (+) | − | |
44 | 24/M | Lymph node and skin | + | + | + | − | + | (+) | − | |
45 | 62/F | Lymph node | + | + | + | − | + | (+) | − | |
46 | 65/M | Lymph node | + | nd | + | (+) | + | + | − | |
47 | 71/M | Bone marrow | + | + | + | − | + | nd | − |
+ indicates all tumor cells are positive; (+), almost all tumor cells are weakly positive; +/−, most of the tumor cells are positive; Scat'rd+, scattered tumor cells are positive; −/+, most of the tumor cells are negative; –, all tumor cells are negative; nd, not done; and na, data not available.