Simulation plan for gene-marking experiments
| A. Test compatibility of mouse and cat parameter values assuming R0 = 100, 300, and 500 |
| λ = 1 replication per 2.5 wk; ν = 1 differentiation per 3.4 wk; α = 1 apoptosis per 20 wk; and μ = 6.9 wk for mouse5 |
| λ = 1 replication per 8.3 wk; ν = 1 differentiation per 12.5 wk; α = 1 apoptosis per 50 wk; and μ = 6.7 wk for cat4 |
| B. Obtain a range for λ, assuming μ = 6.7 wk, R0 = 300, ν = 0.71λ, and α = 0.14λ |
| C. Obtain a range for λ with same assumptions as in B, but R0 = 100 |
| D. Obtain a range for λ with same assumptions as in B, but R0 = 500 |
| E. Obtain a range for μ at best λ, with same assumptions as in B |
| F. Obtain a range for (α, ν) at best λ, with μ = 6.7 wk, R0 = 300, and ν + α = 0.85λ |
| G. Obtain a range for ν + α at best λ with μ = 6.7 wk, R0 = 300, and α = 0.2 ν |
| A. Test compatibility of mouse and cat parameter values assuming R0 = 100, 300, and 500 |
| λ = 1 replication per 2.5 wk; ν = 1 differentiation per 3.4 wk; α = 1 apoptosis per 20 wk; and μ = 6.9 wk for mouse5 |
| λ = 1 replication per 8.3 wk; ν = 1 differentiation per 12.5 wk; α = 1 apoptosis per 50 wk; and μ = 6.7 wk for cat4 |
| B. Obtain a range for λ, assuming μ = 6.7 wk, R0 = 300, ν = 0.71λ, and α = 0.14λ |
| C. Obtain a range for λ with same assumptions as in B, but R0 = 100 |
| D. Obtain a range for λ with same assumptions as in B, but R0 = 500 |
| E. Obtain a range for μ at best λ, with same assumptions as in B |
| F. Obtain a range for (α, ν) at best λ, with μ = 6.7 wk, R0 = 300, and ν + α = 0.85λ |
| G. Obtain a range for ν + α at best λ with μ = 6.7 wk, R0 = 300, and α = 0.2 ν |