Patient demographics and baseline characteristics
| . | No. . |
|---|---|
| Total no. | 295 |
| Male/female (%) | 158 (54)/137 (46) |
| Median age, y (range) | 59 (29-70) |
| Myeloma subtype (%) | |
| IgG | 161 (55) |
| IgA | 79 (27) |
| IgD | 2 (0.7) |
| IgM | 1 (0.3) |
| Bence Jones protein | 44 (15) |
| Nonsecretory | 8 (2) |
| Durie-Salmon disease stage I/II/III, (%) | 15 (5)/133 (45)/147 (50) |
| International Staging System disease stage I/II/III, (%) | 115 (39)/121 (41)/59 (20) |
| β2-microglobulin, mmol/L, median (range) | 26 (1-347) |
| Hemoglobin, g/L, median (range) | 109 (10-168) |
| Creatinine, mmol/L, median (range) | 97 (44-654) |
| Calcium, mmol/L, median (range) | 2.3 (0.6-4.5) |
| C-reactive protein, mg/dL, median (range) | 1.3 (0-148) |
| Albumin, g/L, median (range) | 37 (17-39) |
| % of plasma cells in S-phase, median (range) | 1.2 (0-11.5) |
| Cytogenetics, n = 97 | |
| IgH translocations, (%) | |
| t(4;14) | 8 (8) |
| t(11;14) | 14 (14) |
| t(14;16) | 5 (5) |
| Others | 5 (5) |
| Del(13q) (%) | 30 (31) |
| Del(17p) (%) | 5 (5) |
| High-risk, any t(4;14), t(14;16), or del(17p) (%) | 16 (16) |
| . | No. . |
|---|---|
| Total no. | 295 |
| Male/female (%) | 158 (54)/137 (46) |
| Median age, y (range) | 59 (29-70) |
| Myeloma subtype (%) | |
| IgG | 161 (55) |
| IgA | 79 (27) |
| IgD | 2 (0.7) |
| IgM | 1 (0.3) |
| Bence Jones protein | 44 (15) |
| Nonsecretory | 8 (2) |
| Durie-Salmon disease stage I/II/III, (%) | 15 (5)/133 (45)/147 (50) |
| International Staging System disease stage I/II/III, (%) | 115 (39)/121 (41)/59 (20) |
| β2-microglobulin, mmol/L, median (range) | 26 (1-347) |
| Hemoglobin, g/L, median (range) | 109 (10-168) |
| Creatinine, mmol/L, median (range) | 97 (44-654) |
| Calcium, mmol/L, median (range) | 2.3 (0.6-4.5) |
| C-reactive protein, mg/dL, median (range) | 1.3 (0-148) |
| Albumin, g/L, median (range) | 37 (17-39) |
| % of plasma cells in S-phase, median (range) | 1.2 (0-11.5) |
| Cytogenetics, n = 97 | |
| IgH translocations, (%) | |
| t(4;14) | 8 (8) |
| t(11;14) | 14 (14) |
| t(14;16) | 5 (5) |
| Others | 5 (5) |
| Del(13q) (%) | 30 (31) |
| Del(17p) (%) | 5 (5) |
| High-risk, any t(4;14), t(14;16), or del(17p) (%) | 16 (16) |