Tissue macrophage content
| Macrophage marker . | Wild-type . | macFOXP1tg . | P . |
|---|---|---|---|
| F4/80 | |||
| Lung, cell number | 18.7 ± 7.4 | 17.3 ± 3.9 | .73 |
| Liver, % area | 4.2 ± 1.0 | 4.5 ± 1.3 | .72 |
| Spleen, % area | 30.3 ± 7.3 | 26.1 ± 4.9 | .24 |
| Mac-3 | |||
| Lung, cell number | 31.5 ± 8.2 | 26.2 ± 9.7 | .36 |
| Spleen, % area | 34.4 ± 8.6 | 23.9 ± 3.0 | .051 |
| Macrophage marker . | Wild-type . | macFOXP1tg . | P . |
|---|---|---|---|
| F4/80 | |||
| Lung, cell number | 18.7 ± 7.4 | 17.3 ± 3.9 | .73 |
| Liver, % area | 4.2 ± 1.0 | 4.5 ± 1.3 | .72 |
| Spleen, % area | 30.3 ± 7.3 | 26.1 ± 4.9 | .24 |
| Mac-3 | |||
| Lung, cell number | 31.5 ± 8.2 | 26.2 ± 9.7 | .36 |
| Spleen, % area | 34.4 ± 8.6 | 23.9 ± 3.0 | .051 |
Percentage of F4/80-positive or Mac-3–positive area was quantified using computer-assisted imaging analysis. For lung tissue, the number of F4/80-positive or Mac-3–positive cells per field was counted. Data represent means plus or minus SD from 5 individual mice per genotype.