Table 2

Parameters at baseline in patients with abnormal or normal TCD and predictive factors for abnormal TCD

Parameters at baselinenAbnormal TCD
Normal TCD
OR (95% CI)P
Mean ± SDnMean ± SDn
WBC count, 109/L 327 16.2 ± 5.2 54 13.4 ± 4.6 273 1.12 (1.05-1.19) < .002 
Neutrophil count, 109/L 301 6.8 ± 3.4 51 6.2 ± 3.1 250 1.06 (0.97-1.16) .19 
Hemoglobin level, g/dL 332 7.4 ± 0.8 55 8.1 ± 1.2 277 0.52 (0.38-0.71) < .001 
Hematocrit, % 308 22.4 ± 2.8 51 24.5 ± 3.8 257 0.84 (0.76-0.93) < .001 
MCV, flt 317 83.7 ± 6.3 53 80.2 ± 9.5 264 1.05 (1.01-1.08) .01 
Reticulocyte count, 109/L 303 344.7 ± 146.0 48 278.6 ± 105.3 255 1.004 (1.002-1.007) .001 
LDH level, IU/L 273 1175.6 ± 333.6 38 957.0 ± 343.5 235 1.002 (1.001-1.003) .001 
Platelet count, 109/L 326 360.8 ± 134.7 53 388.2 ± 118.9 273 0.998 (0.996-1.001) .15 
HbF, % 301 11.4 ± 6.2 47 11.4 ± 7.9 254 0.10 (0.96-1.04) .93 
Parameters at baselinenAbnormal TCD
Normal TCD
OR (95% CI)P
Mean ± SDnMean ± SDn
WBC count, 109/L 327 16.2 ± 5.2 54 13.4 ± 4.6 273 1.12 (1.05-1.19) < .002 
Neutrophil count, 109/L 301 6.8 ± 3.4 51 6.2 ± 3.1 250 1.06 (0.97-1.16) .19 
Hemoglobin level, g/dL 332 7.4 ± 0.8 55 8.1 ± 1.2 277 0.52 (0.38-0.71) < .001 
Hematocrit, % 308 22.4 ± 2.8 51 24.5 ± 3.8 257 0.84 (0.76-0.93) < .001 
MCV, flt 317 83.7 ± 6.3 53 80.2 ± 9.5 264 1.05 (1.01-1.08) .01 
Reticulocyte count, 109/L 303 344.7 ± 146.0 48 278.6 ± 105.3 255 1.004 (1.002-1.007) .001 
LDH level, IU/L 273 1175.6 ± 333.6 38 957.0 ± 343.5 235 1.002 (1.001-1.003) .001 
Platelet count, 109/L 326 360.8 ± 134.7 53 388.2 ± 118.9 273 0.998 (0.996-1.001) .15 
HbF, % 301 11.4 ± 6.2 47 11.4 ± 7.9 254 0.10 (0.96-1.04) .93 

Events are defined as abnormally high velocities. Statistically significant P values are indicated in bold.

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