Table 4

Factors affecting overall survival

FactorUnivariate significance (odds ratio; 95% CI)Multivariate significance (odds ratio; 95% CI)
No. of organs .0001 (1.8; 1.3-2.4)  
Performance status* .0001 (4.0; 2.5-6.5) .0001 (3.7; 2.2-6.2) 
Cardiac involvement .026 (2.3; 1.0-3.7) 0.072 (3.8; 0.8-2.5) 
Liver involvement (consensus criteria) .0001 (3.2; 1.6-6.4) .018 (2.2; 1.1-4.5) 
Renal involvement (consensus criteria) 0.28 (1.3; 0.76-2.5)  
Amyloid load on SAP scan 0.28 (1.03; 0.97-1.1)  
Hematologic response 0.42 (0.8; 0.3-1.6)  
Age 0.15 (1.02; 0.9-1.05)  
IgM level 0.54 (0.9; 0.9-1.2)  
Abnormal FLCs 0.41 (1.6; 0.4-5.3)  
FactorUnivariate significance (odds ratio; 95% CI)Multivariate significance (odds ratio; 95% CI)
No. of organs .0001 (1.8; 1.3-2.4)  
Performance status* .0001 (4.0; 2.5-6.5) .0001 (3.7; 2.2-6.2) 
Cardiac involvement .026 (2.3; 1.0-3.7) 0.072 (3.8; 0.8-2.5) 
Liver involvement (consensus criteria) .0001 (3.2; 1.6-6.4) .018 (2.2; 1.1-4.5) 
Renal involvement (consensus criteria) 0.28 (1.3; 0.76-2.5)  
Amyloid load on SAP scan 0.28 (1.03; 0.97-1.1)  
Hematologic response 0.42 (0.8; 0.3-1.6)  
Age 0.15 (1.02; 0.9-1.05)  
IgM level 0.54 (0.9; 0.9-1.2)  
Abnormal FLCs 0.41 (1.6; 0.4-5.3)  

Bold face numbers in columns 2 and 3 indicate significant P values.

*

ECOG performance status 2 or less or more than 2.

Not significant.

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