Table 1 Fascin cells within CD138... | American Society of Hematology

Table 1

Fascin⁺ cells within CD138⁺ cell-infiltrated and noninfiltrated areas

Patient no.	Fascin⁺ cells, mean ± SD
Patient no.	CD138⁺-infiltrated	Noninfiltrated
87	14.6 ± 1.9	0.8 ± 0.8
88	19.4 ± 2.1	0.4 ± 0.8
89	15.4 ± 1.9	0.2 ± 0.4
90	2.2 ± 1.2	1.4 ± 0.8
91	15.8 ± 1.7	0.2 ± 0.4

Patient no.	Fascin⁺ cells, mean ± SD
Patient no.	CD138⁺-infiltrated	Noninfiltrated
87	14.6 ± 1.9	0.8 ± 0.8
88	19.4 ± 2.1	0.4 ± 0.8
89	15.4 ± 1.9	0.2 ± 0.4
90	2.2 ± 1.2	1.4 ± 0.8
91	15.8 ± 1.7	0.2 ± 0.4

Consecutive sections from bone marrow biopsies from 5 patients with recurring MM were stained with CD138 or fascin. Areas with CD138⁺ cell infiltrates were first identified, and infiltrated (myeloma) and noninfiltrated areas (normal) were then re-examined for fascin staining on serial sections. The number of fascin⁺ cell bodies with dendritic projections (excluding capillary endothelial cells) were counted per high-powered field (×1000), and averaged for 5 fields. For all 5 patients combined, P < .001 comparing the number of DCs in the CD138⁺ versus CD138⁻ areas.

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