Table 4 Change in clinical parameters... | American Society of Hematology

Table 4

Change in clinical parameters after HDIT

Assessments	Mean baseline; n = 34	Difference from baseline (CI; P)*
Assessments	Mean baseline; n = 34	Years 1-2	n	Years 3-4	n	Years 5-8	n	Final evaluation;†	n
mRSS (0-51)	30.12	−17.56 (−20.72, −14.40; < .001)	25	−21.24 (−25.42, −17.05; < .001)	21	−21.82 (−25.88, −17.74; < .001)	11	−22.08 (−25.71, −18.45; < .001)	25
mHAQ (0-3)	1.85	−1.26 (−1.60, −0.92; < .001)	23	−1.08 (−1.53, −0.64; < .001)	20	−1.50 (−1.92, −1.09; < .001)	11	−1.03 (−1.40, −0.66; < .001)	26
DLCO_adj, %	60.09	−1.37 (−5.64, 4.98; .60)	27	−3.70 (−9.86, 4.90; .31)	23	−2.27 (−9.69, 5.15; P .51)	11	−6.04 (−12.08, 0.002; .05)	27
FVC, %	71.53	4.48 (0.14, 9.10; .06)	27	2.09 (−5.17, 9.34; .56)	23	10.36 (3.52, 17.20; .007)	11	2.11 (−4.27, 8.49; .50)	27
Creatinine, mg/dL	0.78	0.26 (0.04, 0.47; .02)	26	0.25 (0.07, 0.44; .009)	23	0.13 (0.04, 0.21; .008)	11	0.25 (0.10, 0.40; .003)	27
Ejection fraction, %	63.24	−0.21 (−3.60, 3.19; .90)	24	−2.84 (−5.80, 0.11; .06)	19	−3.85 (−7.22, −0.48; .03)	11	−2.37 (−4.80, 0.07; .06)	27

Assessments	Mean baseline; n = 34	Difference from baseline (CI; P)*
Assessments	Mean baseline; n = 34	Years 1-2	n	Years 3-4	n	Years 5-8	n	Final evaluation;†	n
mRSS (0-51)	30.12	−17.56 (−20.72, −14.40; < .001)	25	−21.24 (−25.42, −17.05; < .001)	21	−21.82 (−25.88, −17.74; < .001)	11	−22.08 (−25.71, −18.45; < .001)	25
mHAQ (0-3)	1.85	−1.26 (−1.60, −0.92; < .001)	23	−1.08 (−1.53, −0.64; < .001)	20	−1.50 (−1.92, −1.09; < .001)	11	−1.03 (−1.40, −0.66; < .001)	26
DLCO_adj, %	60.09	−1.37 (−5.64, 4.98; .60)	27	−3.70 (−9.86, 4.90; .31)	23	−2.27 (−9.69, 5.15; P .51)	11	−6.04 (−12.08, 0.002; .05)	27
FVC, %	71.53	4.48 (0.14, 9.10; .06)	27	2.09 (−5.17, 9.34; .56)	23	10.36 (3.52, 17.20; .007)	11	2.11 (−4.27, 8.49; .50)	27
Creatinine, mg/dL	0.78	0.26 (0.04, 0.47; .02)	26	0.25 (0.07, 0.44; .009)	23	0.13 (0.04, 0.21; .008)	11	0.25 (0.10, 0.40; .003)	27
Ejection fraction, %	63.24	−0.21 (−3.60, 3.19; .90)	24	−2.84 (−5.80, 0.11; .06)	19	−3.85 (−7.22, −0.48; .03)	11	−2.37 (−4.80, 0.07; .06)	27

Mean difference between baseline and last evaluation for 27 patients who survived more than 1 year in the indicated period. Confidence intervals (95%) are within parentheses. Each patient was compared with his own baseline result.

†

Mean difference between baseline and final evaluation after HDIT.

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