Prognostic index based on presence of risk factors
| Characteristic . | Point contribution . | |||
|---|---|---|---|---|
| 0 . | 1 . | 2 . | 3 . | |
| Age, y | — | < 50 | 50-65 | > 65 |
| β-2M, mg/L | < ULN | 1-2 × ULN | > 2 × ULN | — |
| ALC, × 109/L | < 20 | 20-50 | > 50 | — |
| Sex | Female | Male | — | — |
| Rai stage | 0-II | III-IV | — | — |
| No. of involved nodal groups | ≤ 2 | 3 | — | — |
| Characteristic . | Point contribution . | |||
|---|---|---|---|---|
| 0 . | 1 . | 2 . | 3 . | |
| Age, y | — | < 50 | 50-65 | > 65 |
| β-2M, mg/L | < ULN | 1-2 × ULN | > 2 × ULN | — |
| ALC, × 109/L | < 20 | 20-50 | > 50 | — |
| Sex | Female | Male | — | — |
| Rai stage | 0-II | III-IV | — | — |
| No. of involved nodal groups | ≤ 2 | 3 | — | — |
Index score is the sum total of the point contribution for each of the 6 characteristics. An index score of 1-3 indicates low risk; 4-7, intermediate risk; and ≥ 8, high risk.
To convert β-2M from milligrams per liter to nanomoles per liter, multiply milligrams per liter by 85. β-2M indicates β-2 microglobulin; LDH, lactate dehydrogenase; ALC, absolute lymphocyte count; —, not applicable; ULN, upper limit of normal.