Incidence of FLT3/TKD+ patients in specific cytogenetic risk groups and subgroups
| Cytogenetics . | Total no. . | FLT3/TKD−, no. . | FLT3/TKD+, no. . | FLT3/TKD+, % . | P . | FLT3/ITD+, % . |
|---|---|---|---|---|---|---|
| Favorable | 129 | 111 | 18 | 14 | N/A | 12 |
| t(8;21) | 74 | 69 | 5 | 7 | .3 | 15 |
| inv(16) | 55 | 42 | 13 | 24 | .005 | 7 |
| Intermediate | 648 | 575 | 73 | 11 | N/A | 31 |
| Normal | 437 | 386 | 51 | 12 | .4 | 35 |
| del(7q) | 23 | 21 | 2 | 9 | 1.0 | 4 |
| 11q23 | 30 | 28 | 2 | 7 | .8 | 3 |
| +8 | 69 | 61 | 8 | 12 | .8 | 23 |
| +22 | 16 | 13 | 3 | 19 | .2 | 6 |
| Adverse | 105 | 102 | 3 | 3 | N/A | 7 |
| Complex | 61 | 60 | 1 | 2 | .02 | 3 |
| del (5q) | 22 | 20 | 2 | 9 | 1.0 | 0 |
| −5 | 21 | 21 | 0 | 0 | .15 | 0 |
| −7 | 42 | 40 | 2 | 5 | .3 | 2 |
| abn(3q) | 31 | 30 | 1 | 3 | .2 | 16 |
| Unknown | 225 | 192 | 33 | 15 | N/A | 28 |
| Cytogenetics . | Total no. . | FLT3/TKD−, no. . | FLT3/TKD+, no. . | FLT3/TKD+, % . | P . | FLT3/ITD+, % . |
|---|---|---|---|---|---|---|
| Favorable | 129 | 111 | 18 | 14 | N/A | 12 |
| t(8;21) | 74 | 69 | 5 | 7 | .3 | 15 |
| inv(16) | 55 | 42 | 13 | 24 | .005 | 7 |
| Intermediate | 648 | 575 | 73 | 11 | N/A | 31 |
| Normal | 437 | 386 | 51 | 12 | .4 | 35 |
| del(7q) | 23 | 21 | 2 | 9 | 1.0 | 4 |
| 11q23 | 30 | 28 | 2 | 7 | .8 | 3 |
| +8 | 69 | 61 | 8 | 12 | .8 | 23 |
| +22 | 16 | 13 | 3 | 19 | .2 | 6 |
| Adverse | 105 | 102 | 3 | 3 | N/A | 7 |
| Complex | 61 | 60 | 1 | 2 | .02 | 3 |
| del (5q) | 22 | 20 | 2 | 9 | 1.0 | 0 |
| −5 | 21 | 21 | 0 | 0 | .15 | 0 |
| −7 | 42 | 40 | 2 | 5 | .3 | 2 |
| abn(3q) | 31 | 30 | 1 | 3 | .2 | 16 |
| Unknown | 225 | 192 | 33 | 15 | N/A | 28 |
P values are for Fisher exact test for the incidence of TKD mutations in each individual cytogenetic abnormality versus all other known karyotypes.