FLT3/TKD mutations detected in total cohort of 1107 patients
| . | Higher-level mutant, no. . | Lower-level mutant, no. . | Total (% FLT3/TKD+ patients) . |
|---|---|---|---|
| D835Y | 33 | 30 | 63 (50) |
| D835E | 4 | 7 | 11 (9) |
| D835H | 9 | 5 | 14 (11) |
| D835N | 1 | 0 | 1 (1) |
| D835V | 5 | 3 | 8 (6) |
| Δ835 | 1 | 0 | 1 (1) |
| Δ836 | 4 | 11 | 15 (12) |
| ΔDI + InsVIPT | 0 | 1 | 1 (1) |
| D835GP | 1 | 0 | 1 (1) |
| D839G | 1 | 0 | 1 (1) |
| N841I | 1 | 1 | 2 (2) |
| N841K | 1 | 0 | 1 (1) |
| N841Y | 1 | 0 | 1 (1) |
| Unknown | 0 | 7 | 7 (6) |
| . | Higher-level mutant, no. . | Lower-level mutant, no. . | Total (% FLT3/TKD+ patients) . |
|---|---|---|---|
| D835Y | 33 | 30 | 63 (50) |
| D835E | 4 | 7 | 11 (9) |
| D835H | 9 | 5 | 14 (11) |
| D835N | 1 | 0 | 1 (1) |
| D835V | 5 | 3 | 8 (6) |
| Δ835 | 1 | 0 | 1 (1) |
| Δ836 | 4 | 11 | 15 (12) |
| ΔDI + InsVIPT | 0 | 1 | 1 (1) |
| D835GP | 1 | 0 | 1 (1) |
| D839G | 1 | 0 | 1 (1) |
| N841I | 1 | 1 | 2 (2) |
| N841K | 1 | 0 | 1 (1) |
| N841Y | 1 | 0 | 1 (1) |
| Unknown | 0 | 7 | 7 (6) |