Table 2 Successful transplantation of... | American Society of Hematology

Table 2

Successful transplantation of tcirg1 vector-transduced oc/oc FL cells to oc/oc mice and long-term survival of 8 out of 15 treated mice

Mouse	% GFP in vitro	No. of cells	% GFP⁺ cells in PB			Outcome
Mouse	% GFP in vitro	No. of cells	3 wk	6 to 8 wk	12 to 18 wk	Outcome
1	67	1.0 × 10⁶	21	23	NA	S at 8 wk
2	85	1.3 × 10⁶	35	25	NA	S at 8 wk
3	42	2.7 × 10⁶	13	20	37	S at 23 wk
4	55	3.5 × 10⁶	14	49	54	S at 18 wk
5	55	3.5 × 10⁶	8	4	5	† at 24 wk
6	66	1.7 × 10⁶	26	28	33	S at 13 wk
7	66	1.7 × 10⁶	25	22	20	S at 20 wk
8	70	1.6 × 10⁶	29	32	26	SA at 12 wk

Mouse	% GFP in vitro	No. of cells	% GFP⁺ cells in PB			Outcome
Mouse	% GFP in vitro	No. of cells	3 wk	6 to 8 wk	12 to 18 wk	Outcome
1	67	1.0 × 10⁶	21	23	NA	S at 8 wk
2	85	1.3 × 10⁶	35	25	NA	S at 8 wk
3	42	2.7 × 10⁶	13	20	37	S at 23 wk
4	55	3.5 × 10⁶	14	49	54	S at 18 wk
5	55	3.5 × 10⁶	8	4	5	† at 24 wk
6	66	1.7 × 10⁶	26	28	33	S at 13 wk
7	66	1.7 × 10⁶	25	22	20	S at 20 wk
8	70	1.6 × 10⁶	29	32	26	SA at 12 wk

Killed for in vitro osteoclastogenesis, S, X-ray and histology.

NA indicates not applicable; †,died; and SA, still alive.