Table 7 Impact of the number of risk... | American Society of Hematology

Table 7

Impact of the number of risk alleles on susceptibility to chronic myeloid leukemia

Block, gene	Number of risk alleles		Unadjusted		Adjusted
Block, gene	Risk group	Referent group	P	OR (95% CI)	P	OR (95% CI)
2, CSF3			.28		.76
	2	0-1	.84	1.18 (0.69-2.01)	.88	1.22 (0.54-2.73)
	3-4	0-1	.13	1.52 (0.90-2.56)	.55	1.34 (0.62-2.93)
3, VEGFA			.49		.73
	3	0-2	1.00	1.16 (0.68-2.00)	.99	1.15 (0.52-2.54)
	4-6	0-2	.30	1.35 (0.82-2.23)	.49	1.34 (0.64-2.81)
5, BCL2			.10		.23
	2	0-1	.78	1.45 (0.85-2.46)	.95	1.4 (0.62-3.15)
	3-4	0-1	.06	1.84 (1.06-3.22)	.10	2.06 (0.89-4.75)
8, FAS			.29		.58
	2	0-1	.87	1.58 (0.28-8.90)	.94	1.78 (0-1183.53)
	3-4	0-1	.25	2.14 (0.38-11.97)	.71	2.47 (0-1632.03)
13, CASP10			.46		.25
	2-3	0-1	.49	1.02 (0.63-1.65)	.99	1.45 (0.70-2.99)
	4-6	0-1	.21	1.40 (0.77-2.53)	.15	2.12 (0.87-5.17)

Block, gene	Number of risk alleles		Unadjusted		Adjusted
Block, gene	Risk group	Referent group	P	OR (95% CI)	P	OR (95% CI)
2, CSF3			.28		.76
	2	0-1	.84	1.18 (0.69-2.01)	.88	1.22 (0.54-2.73)
	3-4	0-1	.13	1.52 (0.90-2.56)	.55	1.34 (0.62-2.93)
3, VEGFA			.49		.73
	3	0-2	1.00	1.16 (0.68-2.00)	.99	1.15 (0.52-2.54)
	4-6	0-2	.30	1.35 (0.82-2.23)	.49	1.34 (0.64-2.81)
5, BCL2			.10		.23
	2	0-1	.78	1.45 (0.85-2.46)	.95	1.4 (0.62-3.15)
	3-4	0-1	.06	1.84 (1.06-3.22)	.10	2.06 (0.89-4.75)
8, FAS			.29		.58
	2	0-1	.87	1.58 (0.28-8.90)	.94	1.78 (0-1183.53)
	3-4	0-1	.25	2.14 (0.38-11.97)	.71	2.47 (0-1632.03)
13, CASP10			.46		.25
	2-3	0-1	.49	1.02 (0.63-1.65)	.99	1.45 (0.70-2.99)
	4-6	0-1	.21	1.40 (0.77-2.53)	.15	2.12 (0.87-5.17)