Table 5 The outcomes of haplotype... | American Society of Hematology

Table 5

The outcomes of haplotype analysis and its potential association with the susceptibility to chronic myeloid leukemia

Block	Gene	SNP ID			Haplo-type	Frequency			Unadjusted		Adjusted
Block	Gene	SNP1	SNP2	SNP3	Haplo-type	Overall	Case	Control	Omnibus P	Haplotype-specific P	Omnibus P	Haplotype-specific P
2	CSF3	rs25645	rs1042658
		A	C		AC	0.389	0.399	0.380	.15	.58	.55	.28
		G	T		GT	0.338	0.303	0.370		.06*		.64
		G	C		GC	0.273	0.297	0.250		.14		.53
3	VEGFA	rs699947	rs833061	rs2010963
		A	C	G	ACG	0.478	0.525	0.433	.04†	.01†	.30	.12
		C	T	C	CTC	0.335	0.304	0.364		.09*		.28
		C	T	G	CTG	0.187	0.171	0.203		.27		.51
5	BCL2	rs1801018	rs2279115
		A	C		AC	0.483	0.523	0.447	.12	.04†	.16	.09*
		G	A		GA	0.409	0.379	0.436		.12		.06*
		A	A		AA	0.108	0.098	0.117		.43		.74
8	FAS	rs2234767	rs1800682
		G	T		GT	0.528	0.505	0.551	.39	.22	1.00	.65
		G	C		GC	0.357	0.382	0.334		.18		.70
		A	C		AC	0.114	0.113	0.115		.93		.87
13	CASP10	rs13010627	rs13006529	rs3834129
	G	T	A		GTA	0.54	0.518	0.558	.49	.30	.08*	.09*
	G	A	C		GAC	0.386	0.398	0.376		.56		.51
	A	A	C		AAC	0.074	0.084	0.066		.37		.05*

Block	Gene	SNP ID			Haplo-type	Frequency			Unadjusted		Adjusted
Block	Gene	SNP1	SNP2	SNP3	Haplo-type	Overall	Case	Control	Omnibus P	Haplotype-specific P	Omnibus P	Haplotype-specific P
2	CSF3	rs25645	rs1042658
		A	C		AC	0.389	0.399	0.380	.15	.58	.55	.28
		G	T		GT	0.338	0.303	0.370		.06*		.64
		G	C		GC	0.273	0.297	0.250		.14		.53
3	VEGFA	rs699947	rs833061	rs2010963
		A	C	G	ACG	0.478	0.525	0.433	.04†	.01†	.30	.12
		C	T	C	CTC	0.335	0.304	0.364		.09*		.28
		C	T	G	CTG	0.187	0.171	0.203		.27		.51
5	BCL2	rs1801018	rs2279115
		A	C		AC	0.483	0.523	0.447	.12	.04†	.16	.09*
		G	A		GA	0.409	0.379	0.436		.12		.06*
		A	A		AA	0.108	0.098	0.117		.43		.74
8	FAS	rs2234767	rs1800682
		G	T		GT	0.528	0.505	0.551	.39	.22	1.00	.65
		G	C		GC	0.357	0.382	0.334		.18		.70
		A	C		AC	0.114	0.113	0.115		.93		.87
13	CASP10	rs13010627	rs13006529	rs3834129
	G	T	A		GTA	0.54	0.518	0.558	.49	.30	.08*	.09*
	G	A	C		GAC	0.386	0.398	0.376		.56		.51
	A	A	C		AAC	0.074	0.084	0.066		.37		.05*

P < .1.

P < .05.