Original Mycosis Fungoides Cooperative Group TNM classification of cutaneous T-cell lymphoma (CTCL)
| Classification . | Description . |
|---|---|
| T: Skin* | |
| T0 | Clinically and/or histopathologically suspicious lesions |
| T1 | Limited plaques, papules, or eczematous patches covering < 10% of the skin surface |
| T2 | Generalized plaques, papules, or erythematous patches covering ≥ 10% or more of the skin surface |
| T3 | Tumors, one or more |
| T4 | Generalized erythroderma |
| N: Lymph nodes† | |
| N0 | No clinically abnormal peripheral lymph nodes; pathology negative for CTCL |
| N1 | Clinically abnormal peripheral lymph nodes; pathology negative for CTCL |
| N2 | No clinically abnormal peripheral lymph nodes; pathology positive for CTCL |
| N3 | Clinically abnormal peripheral lymph nodes; pathology positive for CTCL |
| B: Peripheral blood | |
| B0 | Atypical circulating cells not present (< 5%) |
| B1 | Atypical circulating cells present (> 5%); record total white blood count and total lymphocyte counts, and number of atypical cells/100 lymphocytes |
| M: Visceral organs | |
| M0 | No visceral organ involvement |
| M1 | Visceral involvement (must have pathology confirmation and organ involved should be specified) |
| Classification . | Description . |
|---|---|
| T: Skin* | |
| T0 | Clinically and/or histopathologically suspicious lesions |
| T1 | Limited plaques, papules, or eczematous patches covering < 10% of the skin surface |
| T2 | Generalized plaques, papules, or erythematous patches covering ≥ 10% or more of the skin surface |
| T3 | Tumors, one or more |
| T4 | Generalized erythroderma |
| N: Lymph nodes† | |
| N0 | No clinically abnormal peripheral lymph nodes; pathology negative for CTCL |
| N1 | Clinically abnormal peripheral lymph nodes; pathology negative for CTCL |
| N2 | No clinically abnormal peripheral lymph nodes; pathology positive for CTCL |
| N3 | Clinically abnormal peripheral lymph nodes; pathology positive for CTCL |
| B: Peripheral blood | |
| B0 | Atypical circulating cells not present (< 5%) |
| B1 | Atypical circulating cells present (> 5%); record total white blood count and total lymphocyte counts, and number of atypical cells/100 lymphocytes |
| M: Visceral organs | |
| M0 | No visceral organ involvement |
| M1 | Visceral involvement (must have pathology confirmation and organ involved should be specified) |
Pathology of T1-4 is diagnostic of a CTCL. When more than 1 T exists, both are recorded and the highest is used for staging (eg, T4(3)).
Record number of sites of abnormal nodes (eg, cervical; left + right), axillary (left + right), inguinal (left + right), epitrochlear, and submandibular/submaxillary.