Table 1 IC 50 values (in nM) of... | American Society of Hematology

Table 1

IC₅₀ values (in nM) of GX015-070 against HMCLs

Cell line	IC₅₀, nM	SD
MM.1S	335	75
MM.1R	390	17
JJN3	132	35
KMS18	60	43
U266	1100	360
SKMM2	150	24
8226s	238	76
UTMC2	173	93
OPM2	282	50
KMS11	282	23
H929	131	25
MY5	90	20
KMS12PE	52	19
MY7	105	11
8226 LR5	164	67

Cell line	IC₅₀, nM	SD
MM.1S	335	75
MM.1R	390	17
JJN3	132	35
KMS18	60	43
U266	1100	360
SKMM2	150	24
8226s	238	76
UTMC2	173	93
OPM2	282	50
KMS11	282	23
H929	131	25
MY5	90	20
KMS12PE	52	19
MY7	105	11
8226 LR5	164	67

Listed are MM cell lines. The concentration of GX015-070 that inhibits 50% viability (IC₅₀) compared to DMSO control after 72-hour incubation with GX015-070 was determined. The data represent means of triplicate or quadruplicate cultures ± SD.

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