Immunophenotypic characterization of genetically modified donor lymphocytes
Patient no. . | CD2 . | CD3 . | CD4 . | CD8 . | CD56 . | CD14 . | CD19 . |
---|---|---|---|---|---|---|---|
1 | NA | 98 | 82 | 18 | NA | NA | NA |
2 | NA | NA | 30 | 62 | NA | NA | NA |
3 | NA | 99 | 16 | 86 | NA | NA | NA |
4 | NA | 91 | 40 | 53 | 8 | NA | NA |
5 | NA | 60 | 39 | 41 | NA | NA | NA |
6 | NA | 100 | 40 | 55 | NA | NA | NA |
7 | NA | 100 | 40 | 60 | NA | NA | NA |
8 | NA | 99 | 19 | 83 | NA | NA | NA |
9 | NA | 81 | 19 | 81 | NA | NA | NA |
10 | 99 | 93 | 15 | 73 | 12 | NA | 0 |
11 | 99 | 98 | 48 | 82 | 11 | 0.1 | 0.2 |
12 | 99 | 98 | 47 | 52 | 6 | 0.20 | 0.6 |
13 | 95.8 | 99 | 14 | 86 | 3 | 0.3 | 0.6 |
14 | 99.2 | 99 | 14 | 86 | 12 | 0.4 | 0.2 |
15 | 99 | 99 | 28 | 72 | 11 | 0.2 | 0 |
16 | 99 | 98 | 31 | 71 | 12 | 1 | 1.8 |
17 | 99.3 | 98 | 38 | 60 | 19 | 0.3 | 0.2 |
18 | 99 | 98 | 11 | 85 | 15 | 0 | 0 |
19 | 99.1 | 97.9 | 42 | 57 | 1 | 0.4 | 2.1 |
20 | 99 | 100 | 12 | 87 | 11 | 0.4 | 3.8 |
21 | 99 | 83 | 14 | 68 | 9 | 1.2 | 0.9 |
22 | 99.8 | 98 | 27 | 73 | 2 | 0.1 | 0.3 |
23 | 99 | 99 | 21 | 78 | 10 | 0.1 | 0.3 |
Median | 99 | 98 | 24 | 72.5 | 10.5 | 0.3 | 0 |
Range | 95.8-99.8 | 81-100 | 11-82 | 18-87 | 1-19 | 0.1-1.2 | 0-3.8 |
Patient no. . | CD2 . | CD3 . | CD4 . | CD8 . | CD56 . | CD14 . | CD19 . |
---|---|---|---|---|---|---|---|
1 | NA | 98 | 82 | 18 | NA | NA | NA |
2 | NA | NA | 30 | 62 | NA | NA | NA |
3 | NA | 99 | 16 | 86 | NA | NA | NA |
4 | NA | 91 | 40 | 53 | 8 | NA | NA |
5 | NA | 60 | 39 | 41 | NA | NA | NA |
6 | NA | 100 | 40 | 55 | NA | NA | NA |
7 | NA | 100 | 40 | 60 | NA | NA | NA |
8 | NA | 99 | 19 | 83 | NA | NA | NA |
9 | NA | 81 | 19 | 81 | NA | NA | NA |
10 | 99 | 93 | 15 | 73 | 12 | NA | 0 |
11 | 99 | 98 | 48 | 82 | 11 | 0.1 | 0.2 |
12 | 99 | 98 | 47 | 52 | 6 | 0.20 | 0.6 |
13 | 95.8 | 99 | 14 | 86 | 3 | 0.3 | 0.6 |
14 | 99.2 | 99 | 14 | 86 | 12 | 0.4 | 0.2 |
15 | 99 | 99 | 28 | 72 | 11 | 0.2 | 0 |
16 | 99 | 98 | 31 | 71 | 12 | 1 | 1.8 |
17 | 99.3 | 98 | 38 | 60 | 19 | 0.3 | 0.2 |
18 | 99 | 98 | 11 | 85 | 15 | 0 | 0 |
19 | 99.1 | 97.9 | 42 | 57 | 1 | 0.4 | 2.1 |
20 | 99 | 100 | 12 | 87 | 11 | 0.4 | 3.8 |
21 | 99 | 83 | 14 | 68 | 9 | 1.2 | 0.9 |
22 | 99.8 | 98 | 27 | 73 | 2 | 0.1 | 0.3 |
23 | 99 | 99 | 21 | 78 | 10 | 0.1 | 0.3 |
Median | 99 | 98 | 24 | 72.5 | 10.5 | 0.3 | 0 |
Range | 95.8-99.8 | 81-100 | 11-82 | 18-87 | 1-19 | 0.1-1.2 | 0-3.8 |
Immunophenotype of TK+ cells analyzed at the end of the procedure by FACS analysis immediately before cryopreservation.
NA indicates data not available.