Multiple Cox regression: best prognostic model for survival probabilities
| Model B . | No./died† . | Estimation of coefficient β . | Standard deviation of estimated β . | Wald's χ† statistic . | P value . | Hazard ratio . |
|---|---|---|---|---|---|---|
| Deletion status | 335/130 | — | — | 9.784 (2 df) | .007 | — |
| No | 276/110 | Baseline | — | — | — | — |
| One side of breakpoint | 38/7 | −0.870 | 0.391 | 4.944 | .026 | 0.419 |
| Whole breakpoint | 21/13 | 0.623 | 0.302 | 4.251 | .039 | 1.864 |
| Age, fully completed years | 335/130 | 0.018 | 0.007 | 5.627 (1 df) | .018 | 1.018 |
| Spleen enlargement, cm | 335/130 | 0.058 | 0.016 | 13.519 (1 df) | < .001 | 1.059 |
| Model B . | No./died† . | Estimation of coefficient β . | Standard deviation of estimated β . | Wald's χ† statistic . | P value . | Hazard ratio . |
|---|---|---|---|---|---|---|
| Deletion status | 335/130 | — | — | 9.784 (2 df) | .007 | — |
| No | 276/110 | Baseline | — | — | — | — |
| One side of breakpoint | 38/7 | −0.870 | 0.391 | 4.944 | .026 | 0.419 |
| Whole breakpoint | 21/13 | 0.623 | 0.302 | 4.251 | .039 | 1.864 |
| Age, fully completed years | 335/130 | 0.018 | 0.007 | 5.627 (1 df) | .018 | 1.018 |
| Spleen enlargement, cm | 335/130 | 0.058 | 0.016 | 13.519 (1 df) | < .001 | 1.059 |
Survival times of patients with imatinib or stem cell transplantation in the first chronic phase were censored.
df indicates degrees of freedom; —, not applicable.
For the candidate variables deletion status, age, spleen enlargement, blasts, basophils, eosinophils, platelet count, haemoglobin, white blood cell count, and sex, 335 patients with complete cases were available of whom 130 patients died.