Multiple Cox regression: deletion status and Hasford score as independent prognostic factors for survival probabilities
| Model A . | No./died† . | Estimation of coefficient β . | Standard deviation of estimated β . | Wald's χ2 statistic . | Pvalue . | Hazard ratio . |
|---|---|---|---|---|---|---|
| Deletion status | 338/131 | — | — | 10.084 (2 df) | .007 | — |
| No | 279/111 | Baseline | — | — | — | — |
| One side of breakpoint | 38/7 | −0.896 | 0.394 | 5.163 | .023 | 0.408 |
| Whole breakpoint | 21/13 | 0.620 | 0.297 | 4.343 | .037 | 1.859 |
| Hasford score | 338/131 | — | — | 8.966 (2 df) | .011 | — |
| Low | 132/36 | −0.279 | 0.204 | 1.876 | .17 | 0.756 |
| Intermediate | 166/73 | Baseline | — | — | — | — |
| High | 40/22 | 0.546 | 0.249 | 4.818 | .028 | 1.727 |
| Model A . | No./died† . | Estimation of coefficient β . | Standard deviation of estimated β . | Wald's χ2 statistic . | Pvalue . | Hazard ratio . |
|---|---|---|---|---|---|---|
| Deletion status | 338/131 | — | — | 10.084 (2 df) | .007 | — |
| No | 279/111 | Baseline | — | — | — | — |
| One side of breakpoint | 38/7 | −0.896 | 0.394 | 5.163 | .023 | 0.408 |
| Whole breakpoint | 21/13 | 0.620 | 0.297 | 4.343 | .037 | 1.859 |
| Hasford score | 338/131 | — | — | 8.966 (2 df) | .011 | — |
| Low | 132/36 | −0.279 | 0.204 | 1.876 | .17 | 0.756 |
| Intermediate | 166/73 | Baseline | — | — | — | — |
| High | 40/22 | 0.546 | 0.249 | 4.818 | .028 | 1.727 |
Survival times of patients with imatinib or stem cell transplantation in first chronic phase were censored.
df indicates degrees of freedom; —, not applicable.
For one patient, the Hasford score was not evaluable.