Patient description
| Patient no. . | Disease stage . | Response to therapy . | Response duration, mo . | BCR/ABL positivity, % . | BCR/ABL mutations . | FTase mutations . |
|---|---|---|---|---|---|---|
| 1 | AP | Partial HR | 10 | 100 | E292V | I107V |
| 2 | AP | None | 0 | 100 | G250E, M351T | Y361L C95R |
| 3 | CP | Partial CR | <15 | 88.33 | None | None |
| 4 | CP | Partial HR | 12 | 30.24 | None | None |
| 5 | AP | None | 0 | NA | None | None |
| 6 | CP | None | 0 | 100 | None | None |
| 7 | CP | None | 0 | 100 | G250E | None |
| 8 | AP | CHR | 2 | NA | F359V | None |
| 9 | AP | SD | 3 | 9.148 | E279L | None |
| 10* | NA | NA | NA | NA | NA | Y361H |
| Patient no. . | Disease stage . | Response to therapy . | Response duration, mo . | BCR/ABL positivity, % . | BCR/ABL mutations . | FTase mutations . |
|---|---|---|---|---|---|---|
| 1 | AP | Partial HR | 10 | 100 | E292V | I107V |
| 2 | AP | None | 0 | 100 | G250E, M351T | Y361L C95R |
| 3 | CP | Partial CR | <15 | 88.33 | None | None |
| 4 | CP | Partial HR | 12 | 30.24 | None | None |
| 5 | AP | None | 0 | NA | None | None |
| 6 | CP | None | 0 | 100 | None | None |
| 7 | CP | None | 0 | 100 | G250E | None |
| 8 | AP | CHR | 2 | NA | F359V | None |
| 9 | AP | SD | 3 | 9.148 | E279L | None |
| 10* | NA | NA | NA | NA | NA | Y361H |
AP indicates accelerated phase; CP, chronic phase; CHR, complete hematologic response; SD, stable disease; and NA, not available.
Patient 10 decided not to enter the study. Only a baseline sample was collected.