Table 2

Characteristics of all patients with clinically relevant inhibitors

All inhibitorsRangeHigh-titer* inhibitorsRangeLow-titer inhibitorsRange
No. patients (%) 87 (24) NA 69 (79) NA 18 (21) NA 
Median no. exposure days at inhibitor development (IQR) 14 (8-21) 2-50 14 (8-22) 2-50 14 (6-20) 2-43 
Median age at inhibitor development, mo (IQR) 15 (10-22) 0.3-79 15 (10-22) 0.3-79 17 (10-26) 10-47 
Median duration between first exposure day and inhibitor development, mo (IQR) 5 (2-12) 0.2-60 5 (2-11) 0.2-60 8 (4-18) 1-47 
All inhibitorsRangeHigh-titer* inhibitorsRangeLow-titer inhibitorsRange
No. patients (%) 87 (24) NA 69 (79) NA 18 (21) NA 
Median no. exposure days at inhibitor development (IQR) 14 (8-21) 2-50 14 (8-22) 2-50 14 (6-20) 2-43 
Median age at inhibitor development, mo (IQR) 15 (10-22) 0.3-79 15 (10-22) 0.3-79 17 (10-26) 10-47 
Median duration between first exposure day and inhibitor development, mo (IQR) 5 (2-12) 0.2-60 5 (2-11) 0.2-60 8 (4-18) 1-47 

NA indicates not applicable

*High-titer inhibitor was defined as clinically relevant inhibitor with a peak titer of at least 5 BU/mL.

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