Inhibitor eradication and patient survival following immunosuppression
| Treatment group . | No. of patients analyzed for inhibitor eradication . | No. of remission events (% of group) . | Median time to remission, d (95% CI) . | No. of patients analyzed for survival . | No. of deaths from any cause (% of group) . | Median time presentation to death from any cause, d (95% CI) . |
|---|---|---|---|---|---|---|
| Steroids alone | 34 | 26 (76) | 49 (31-62) | 38 | 18 (47) | 767 (148-1122) |
| Steroids and cytotoxics started together | 45 | 35 (78) | 39 (34-57) | 48 | 18 (38) | 975 (526-1176) |
| Steroids and cytotoxics regardless of order started | 81 | 61 (75) | 56 (40-79) | 89 | 37 (42) | 870 (526-1176) |
| Cytotoxics alone | 7 | 4 (57) | 273* | 7 | 1 | Not defined |
| Treatment group . | No. of patients analyzed for inhibitor eradication . | No. of remission events (% of group) . | Median time to remission, d (95% CI) . | No. of patients analyzed for survival . | No. of deaths from any cause (% of group) . | Median time presentation to death from any cause, d (95% CI) . |
|---|---|---|---|---|---|---|
| Steroids alone | 34 | 26 (76) | 49 (31-62) | 38 | 18 (47) | 767 (148-1122) |
| Steroids and cytotoxics started together | 45 | 35 (78) | 39 (34-57) | 48 | 18 (38) | 975 (526-1176) |
| Steroids and cytotoxics regardless of order started | 81 | 61 (75) | 56 (40-79) | 89 | 37 (42) | 870 (526-1176) |
| Cytotoxics alone | 7 | 4 (57) | 273* | 7 | 1 | Not defined |
Comparison of patients treated with steroids alone and those treated with steroids and cytotoxics started together at presentation revealed no significant difference for inhibitor eradication or death. Comparison of steroid-treated patients with all patients treated with steroids and cytotoxics, irrespective of the order of starting also did not show any difference for inhibitor eradication or survival.
Too few patients to allow valid calculation of confidence intervals.