Table 5

List of the 30 classifier genes distinguishing S aureus from E coli infections

Function, geneSignificance
S aureus to E coli 
    Signal transduction 
        CXCL1 0.00106 
        JAG1 0.00158 
        RGS2 0.00027 
    Metabolism 
        GAPD 0.00044 
        PPIB 0.00044 
        PSMA7 0.00106 
        MMP9 0.00837 
        p44S10 0.00158 
    Protein targeting 
        TRAM2 0.00384 
    Intracellular protein transport 
        SEC24C 4.92 × 10−5 
    Miscellaneous 
        ACTG1 0.00622 
        CGI-96 0.00454 
        MGC2963 0.00158 
        STAU 4.92 × 10−5 
        STAU 4.92 × 10−5 
E coli to S aureus 
    Intracellular signaling 
        RASA1 1.20 × 10−5 
        SNX4 4.92 × 10−5 
        MAP4K4 0.000693 
    Regulation of translational initiation 
        AF1Q 0.00106 
        EIF5B 0.00106 
    Regulation of transcription 
        SMAD2 0.00044 
    Cell adhesion 
        JUP 0.00158 
    Metabolism 
        PP 4.92 × 10−5 
        MAN1C1 0.00016 
    Miscellaneous 
        FLJ10287 4.92 × 10−5 
        FLJ20152 0.00622 
        LRRN3 1.20 × 10−5 
        LRRN3 0.00027 
        SGPP1 0.00158 
        UBAP2L 2.12 × 10−6 
Function, geneSignificance
S aureus to E coli 
    Signal transduction 
        CXCL1 0.00106 
        JAG1 0.00158 
        RGS2 0.00027 
    Metabolism 
        GAPD 0.00044 
        PPIB 0.00044 
        PSMA7 0.00106 
        MMP9 0.00837 
        p44S10 0.00158 
    Protein targeting 
        TRAM2 0.00384 
    Intracellular protein transport 
        SEC24C 4.92 × 10−5 
    Miscellaneous 
        ACTG1 0.00622 
        CGI-96 0.00454 
        MGC2963 0.00158 
        STAU 4.92 × 10−5 
        STAU 4.92 × 10−5 
E coli to S aureus 
    Intracellular signaling 
        RASA1 1.20 × 10−5 
        SNX4 4.92 × 10−5 
        MAP4K4 0.000693 
    Regulation of translational initiation 
        AF1Q 0.00106 
        EIF5B 0.00106 
    Regulation of transcription 
        SMAD2 0.00044 
    Cell adhesion 
        JUP 0.00158 
    Metabolism 
        PP 4.92 × 10−5 
        MAN1C1 0.00016 
    Miscellaneous 
        FLJ10287 4.92 × 10−5 
        FLJ20152 0.00622 
        LRRN3 1.20 × 10−5 
        LRRN3 0.00027 
        SGPP1 0.00158 
        UBAP2L 2.12 × 10−6 

Genes are grouped functionally based on ontologies, and levels of significance are shown. Full details are available in Table S6.

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