List of the 35 classifier genes distinguishing influenza A from bacterial infections
| Function, gene . | Significance . |
|---|---|
| Influenza to bacteria | |
| Response to virus | |
| cig5 | 1.46 × 10−5 |
| DNAPTP6 | 4.52 × 10−6 |
| IFI27 | 4.52 × 10−6 |
| IFI35 | 0.00033 |
| IFI44 | 0.00023 |
| IFI44 | 0.00015 |
| OAS1 | 6.52 × 10−5 |
| Immune response | |
| BST2 | 4.08 × 10−5 |
| G1P2 | 0.000101 |
| LY6E | 8.28 × 10−6 |
| MX1 | 6.52 × 10−5 |
| Antiapoptosis | |
| SON | 0.00067 |
| Cell growth or maintenance | |
| TRIM14 | 4.08 × 10−5 |
| Miscellaneous | |
| APOBEC3C | 2.35 × 10−7 |
| C1orf29 | 0.00015 |
| FLJ20035 | 4.08 × 10−5 |
| FLJ38348 | 0.00128 |
| HSXIAPAF1 | 4.52 × 10−6 |
| KIAA0152 | 2.48 × 10−5 |
| PHACTR2 | 9.34 × 10−8 |
| USP18 | 1.46 × 10−5 |
| ZBP1 | 5.41 × 10−7 |
| Bacteria to influenza | |
| Translational elongation | |
| EEF1G | 4.52 × 10−6 |
| EEF1G | 2.35 × 10−6 |
| Regulation of translational initiation | |
| EIF3S5 | 9.34 × 10−8 |
| EIF3S7 | 2.35 × 10−7 |
| EIF4B | 1.16 × 10−6 |
| Protein biosynthesis | |
| QARS | 5.41 × 10−7 |
| RPL31 | 4.52 × 10−6 |
| RPL4 | 2.35 × 10−7 |
| Regulation of transcription | |
| PFDN5 | 5.41 × 10−7 |
| Cell adhesion | |
| CD44 | 2.35 × 10−7 |
| Metabolism | |
| HADHA | 4.08 × 10−5 |
| PCBP2 | 9.34 × 10−8 |
| Miscellaneous | |
| dJ507I15.1 | 6.52 × 10−5 |
| Function, gene . | Significance . |
|---|---|
| Influenza to bacteria | |
| Response to virus | |
| cig5 | 1.46 × 10−5 |
| DNAPTP6 | 4.52 × 10−6 |
| IFI27 | 4.52 × 10−6 |
| IFI35 | 0.00033 |
| IFI44 | 0.00023 |
| IFI44 | 0.00015 |
| OAS1 | 6.52 × 10−5 |
| Immune response | |
| BST2 | 4.08 × 10−5 |
| G1P2 | 0.000101 |
| LY6E | 8.28 × 10−6 |
| MX1 | 6.52 × 10−5 |
| Antiapoptosis | |
| SON | 0.00067 |
| Cell growth or maintenance | |
| TRIM14 | 4.08 × 10−5 |
| Miscellaneous | |
| APOBEC3C | 2.35 × 10−7 |
| C1orf29 | 0.00015 |
| FLJ20035 | 4.08 × 10−5 |
| FLJ38348 | 0.00128 |
| HSXIAPAF1 | 4.52 × 10−6 |
| KIAA0152 | 2.48 × 10−5 |
| PHACTR2 | 9.34 × 10−8 |
| USP18 | 1.46 × 10−5 |
| ZBP1 | 5.41 × 10−7 |
| Bacteria to influenza | |
| Translational elongation | |
| EEF1G | 4.52 × 10−6 |
| EEF1G | 2.35 × 10−6 |
| Regulation of translational initiation | |
| EIF3S5 | 9.34 × 10−8 |
| EIF3S7 | 2.35 × 10−7 |
| EIF4B | 1.16 × 10−6 |
| Protein biosynthesis | |
| QARS | 5.41 × 10−7 |
| RPL31 | 4.52 × 10−6 |
| RPL4 | 2.35 × 10−7 |
| Regulation of transcription | |
| PFDN5 | 5.41 × 10−7 |
| Cell adhesion | |
| CD44 | 2.35 × 10−7 |
| Metabolism | |
| HADHA | 4.08 × 10−5 |
| PCBP2 | 9.34 × 10−8 |
| Miscellaneous | |
| dJ507I15.1 | 6.52 × 10−5 |
Genes are grouped functionally based on ontologies, and levels of significance are shown. Full details are available in Table S3.