Table 1

Differential blood counts are normal in the TNF-α receptor-null mice

Cell typeLeukocyte number, × 10−3 cells/μL blood
WTp55−/−p75−/−D−/−
WBCs 6.8 ± 0.85 8.7 ± 0.9 7.1 ± 1.1 10.6 ± 2.4 
Neutrophils 0.43 ± 0.18 0.34 ± 0.14 0.46 ± 0.05 0.64 ± 0.28 
Lymphocytes 5.75 ± 0.73 7.9 ± 0.84 6.3 ± 1.0 9.7 ± 2.30 
Monocytes 0.15 ± 0.08 0.10 ± 0.01 0.11 ± 0.01 0.14 ± 0.08 
Eosinophils 0.13 ± 0.05 0.23 ± 0.01 0.23 ± 0.01 0.28 ± 0.03 
Cell typeLeukocyte number, × 10−3 cells/μL blood
WTp55−/−p75−/−D−/−
WBCs 6.8 ± 0.85 8.7 ± 0.9 7.1 ± 1.1 10.6 ± 2.4 
Neutrophils 0.43 ± 0.18 0.34 ± 0.14 0.46 ± 0.05 0.64 ± 0.28 
Lymphocytes 5.75 ± 0.73 7.9 ± 0.84 6.3 ± 1.0 9.7 ± 2.30 
Monocytes 0.15 ± 0.08 0.10 ± 0.01 0.11 ± 0.01 0.14 ± 0.08 
Eosinophils 0.13 ± 0.05 0.23 ± 0.01 0.23 ± 0.01 0.28 ± 0.03 

Blood (200 μL) from each mouse was injected into an ADVIA 120 Hematology System (Bayer Diagnostics, Tarrytown, NY). For each genotype, 4 samples were analyzed and the standard deviation is presented.

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