Immunohistochemical analysis of Drm/gremlin expression in human lung tumors
| Lung tumors . | No. of tumors with the indicated Drm/gremlin immunostaining intensity . | |||||
|---|---|---|---|---|---|---|
| Cancer-cell immunostaining . | Endothelial-cell immunostaining . | |||||
| − . | + . | ++ . | − . | + . | ++ . | |
| Adenocarcinomas | 4 | 1 | 0 | 0 | 0 | 5 |
| Squamous-cell carcinomas | 3 | 2 | 0 | 0 | 1 | 4 |
| Lung tumors . | No. of tumors with the indicated Drm/gremlin immunostaining intensity . | |||||
|---|---|---|---|---|---|---|
| Cancer-cell immunostaining . | Endothelial-cell immunostaining . | |||||
| − . | + . | ++ . | − . | + . | ++ . | |
| Adenocarcinomas | 4 | 1 | 0 | 0 | 0 | 5 |
| Squamous-cell carcinomas | 3 | 2 | 0 | 0 | 1 | 4 |
Paraffin-embedded human lung cancer specimens (for each type listed in the table, n = 5) were analyzed for Drm/gremlin expression by immunostaining. Cancer cells and endothelial cells of each specimen were scored for Drm/gremlin immunoreactivity on an arbitrary scale: − indicates negative; +, weak staining; ++, strong staining.