Univariate analysis of probability of 5-year overall survival (OS) in 258 pediatric patients with −7 or del(7q) ± other
| Variable . | No. of patients . | Probability 5-year OS, % . | 95% CI . |
|---|---|---|---|
| Karyotype | |||
| del(7q) favorable | 21 | 75 | 57-93 |
| del(7q) no favorable | 65 | 44 | 30-58 |
| −7 excl inv(3), −5/5q-, + 21 | 149 | 35 | 27-43 |
| −7 inv(3), −5/5q-, or + 21 | 23 | 5 | 0-13 |
| Age | |||
| Younger than 6 y | 99 | 46 | 36-56 |
| 6 y to younger than 12 y | 93 | 30 | 20-40 |
| At least 12 y | 66 | 35 | 24-46 |
| WBC count | |||
| Less than 20 × 109/L | 147 | 43 | 35-51 |
| At least 20 × 109/L | 87 | 33 | 22-44 |
| Year of diagnosis | |||
| 1997 or later | 112 | 48 | 38-58 |
| Before 1997 | 146 | 33 | 25-41 |
| Sex | |||
| Male | 145 | 36 | 28-44 |
| Female | 113 | 40 | 30-50 |
| Variable . | No. of patients . | Probability 5-year OS, % . | 95% CI . |
|---|---|---|---|
| Karyotype | |||
| del(7q) favorable | 21 | 75 | 57-93 |
| del(7q) no favorable | 65 | 44 | 30-58 |
| −7 excl inv(3), −5/5q-, + 21 | 149 | 35 | 27-43 |
| −7 inv(3), −5/5q-, or + 21 | 23 | 5 | 0-13 |
| Age | |||
| Younger than 6 y | 99 | 46 | 36-56 |
| 6 y to younger than 12 y | 93 | 30 | 20-40 |
| At least 12 y | 66 | 35 | 24-46 |
| WBC count | |||
| Less than 20 × 109/L | 147 | 43 | 35-51 |
| At least 20 × 109/L | 87 | 33 | 22-44 |
| Year of diagnosis | |||
| 1997 or later | 112 | 48 | 38-58 |
| Before 1997 | 146 | 33 | 25-41 |
| Sex | |||
| Male | 145 | 36 | 28-44 |
| Female | 113 | 40 | 30-50 |