Genes overexpressed in CD30− PTCL-u compared to CD30+ PTCL-u
| Gene symbol . | Gene title . | Fold difference of geometric means . |
|---|---|---|
| T-cell activation | ||
| CD28 | CD28 antigen (Tp44) | 6.19 |
| ITK | IL-2-inducible T-cell kinase | 3.68 |
| CD69 | CD69 antigen (p60, early T-cell activation antigen) | 3.31 |
| CD52 | CD52 antigen (CAMPATH-1 antigen) | 2.97 |
| LCK | Lymphocyte-specific protein tyrosine kinase | 2.54 |
| FYN | FYN oncogene related to SRC, FGR, YES | 2.53 |
| NFATC3 | Nuclear factor of activated T cells, cytoplasmic, calcineurin-dependent 3 | 1.67 |
| Transcription | ||
| AFF3 | AF4/FMR2 family, member 3 | 7.86 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 5.48 |
| FOXP1 | Forkhead box P1 | 2.57 |
| Apoptosis | ||
| BTG1 | B-cell translocation gene 1, antiproliferative | 4.05 |
| FAIM3 | Fas apoptotic inhibitory molecule 3 | 3.91 |
| PDCD4 | Programmed cell death 4 (neoplastic transformation inhibitor) | 2.45 |
| IL24 | Interleukin 24 | 2.42 |
| MLL5 | Myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila) | 1.59 |
| FLJ39616 | Apoptosis-related protein PNAS-1 | 1.47 |
| Lymphocyte migration | ||
| IL16 | Interleukin 16 (lymphocyte chemoattractant factor) | 2.71 |
| CCR6 | Chemokine (C-C motif) receptor 6 | 2.64 |
| SELL | Selectin L (lymphocyte adhesion molecule 1) | 2.77 |
| Others | ||
| LTB | Lymphotoxin beta (TNF superfamily, member 3) | 2.61 |
| CCND3 | Cyclin D3 | 1.83 |
| Gene symbol . | Gene title . | Fold difference of geometric means . |
|---|---|---|
| T-cell activation | ||
| CD28 | CD28 antigen (Tp44) | 6.19 |
| ITK | IL-2-inducible T-cell kinase | 3.68 |
| CD69 | CD69 antigen (p60, early T-cell activation antigen) | 3.31 |
| CD52 | CD52 antigen (CAMPATH-1 antigen) | 2.97 |
| LCK | Lymphocyte-specific protein tyrosine kinase | 2.54 |
| FYN | FYN oncogene related to SRC, FGR, YES | 2.53 |
| NFATC3 | Nuclear factor of activated T cells, cytoplasmic, calcineurin-dependent 3 | 1.67 |
| Transcription | ||
| AFF3 | AF4/FMR2 family, member 3 | 7.86 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 5.48 |
| FOXP1 | Forkhead box P1 | 2.57 |
| Apoptosis | ||
| BTG1 | B-cell translocation gene 1, antiproliferative | 4.05 |
| FAIM3 | Fas apoptotic inhibitory molecule 3 | 3.91 |
| PDCD4 | Programmed cell death 4 (neoplastic transformation inhibitor) | 2.45 |
| IL24 | Interleukin 24 | 2.42 |
| MLL5 | Myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila) | 1.59 |
| FLJ39616 | Apoptosis-related protein PNAS-1 | 1.47 |
| Lymphocyte migration | ||
| IL16 | Interleukin 16 (lymphocyte chemoattractant factor) | 2.71 |
| CCR6 | Chemokine (C-C motif) receptor 6 | 2.64 |
| SELL | Selectin L (lymphocyte adhesion molecule 1) | 2.77 |
| Others | ||
| LTB | Lymphotoxin beta (TNF superfamily, member 3) | 2.61 |
| CCND3 | Cyclin D3 | 1.83 |
A complete list of genes is available in Table S4.