Table 2

Risk stratification in polycythemia vera based on thrombotic risk

Risk categoryAge older than 60 y or history of thrombosisCardiovascular risk factors*
Low No No 
Intermediate No Yes 
High Yes — 
Risk categoryAge older than 60 y or history of thrombosisCardiovascular risk factors*
Low No No 
Intermediate No Yes 
High Yes — 

Extreme thrombocytosis (platelet count > 1500 × 109/L) is a risk factor for bleeding. Its role as a risk factor for thrombosis is uncertain. Increasing leukocyte count has been identified as a novel risk factor for thrombosis, but confirmation is required.

— indicates not applicable.

*

Hypertension, hypercholesterolemia, diabetes, smoking (see “Other risk factors”).

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