Absolute sizes of myeloid, erythroid, and lymphoid populations in hematopoietic organs
| Hematopoietic organ . | Control, × 106 cells . | RhoH−/−, × 106 cells . | P . | ||
|---|---|---|---|---|---|
| Mean . | SD . | Mean . | SD . | ||
| Bone marrow | |||||
| Mac1+ Gr-1+ | 14.849 | 2.357 | 14.889 | 1.501 | — |
| Mac1+ Gr-1− | 1.679 | 0.594 | 1.360 | 0.466 | — |
| Ter119+ | 7.131 | 4.622 | 6.733 | 4.560 | — |
| NK1.1+ | 0.151 | 0.100 | 0.355 | 0.092 | < .01 |
| CD4+ | 0.218 | 0.123 | 0.101 | 0.021 | < .05 |
| CD8+ | 0.225 | 0.159 | 0.054 | 0.007 | < .05 |
| B220+IgM− | 2.377 | 1.110 | 2.620 | 0.745 | — |
| B220+IgM+ | 1.602 | 0.645 | 2.084 | 0.591 | — |
| B220+IgM+IgD+ | 0.740 | 0.183 | 0.971 | 0.422 | — |
| Spleen | |||||
| Mac1+ Gr-1+ | 10.192 | 3.666 | 9.721 | 4.169 | — |
| Mac1+ Gr-1− | 5.879 | 1.351 | 8.971 | 2.366 | < .05 |
| Ter119+ | 24.934 | 5.423 | 26.361 | 8.124 | — |
| NK1.1+ | 2.791 | 1.337 | 7.816 | 2.617 | < .01 |
| CD4+ | 64.082 | 7.282 | 23.741 | 5.426 | < .001 |
| CD8+ | 27.418 | 3.342 | 7.500 | 0.743 | < .001 |
| IgD+ | 97.934 | 12.041 | 89.384 | 7.611 | — |
| Lymph nodes | |||||
| CD4+ | 4.163 | 3.649 | 1.855 | 1.105 | — |
| CD8+ | 1.603 | 1.506 | 0.281 | 0.226 | — |
| IgM+IgD+ | 1.077 | 0.646 | 0.959 | 0.434 | — |
| Hematopoietic organ . | Control, × 106 cells . | RhoH−/−, × 106 cells . | P . | ||
|---|---|---|---|---|---|
| Mean . | SD . | Mean . | SD . | ||
| Bone marrow | |||||
| Mac1+ Gr-1+ | 14.849 | 2.357 | 14.889 | 1.501 | — |
| Mac1+ Gr-1− | 1.679 | 0.594 | 1.360 | 0.466 | — |
| Ter119+ | 7.131 | 4.622 | 6.733 | 4.560 | — |
| NK1.1+ | 0.151 | 0.100 | 0.355 | 0.092 | < .01 |
| CD4+ | 0.218 | 0.123 | 0.101 | 0.021 | < .05 |
| CD8+ | 0.225 | 0.159 | 0.054 | 0.007 | < .05 |
| B220+IgM− | 2.377 | 1.110 | 2.620 | 0.745 | — |
| B220+IgM+ | 1.602 | 0.645 | 2.084 | 0.591 | — |
| B220+IgM+IgD+ | 0.740 | 0.183 | 0.971 | 0.422 | — |
| Spleen | |||||
| Mac1+ Gr-1+ | 10.192 | 3.666 | 9.721 | 4.169 | — |
| Mac1+ Gr-1− | 5.879 | 1.351 | 8.971 | 2.366 | < .05 |
| Ter119+ | 24.934 | 5.423 | 26.361 | 8.124 | — |
| NK1.1+ | 2.791 | 1.337 | 7.816 | 2.617 | < .01 |
| CD4+ | 64.082 | 7.282 | 23.741 | 5.426 | < .001 |
| CD8+ | 27.418 | 3.342 | 7.500 | 0.743 | < .001 |
| IgD+ | 97.934 | 12.041 | 89.384 | 7.611 | — |
| Lymph nodes | |||||
| CD4+ | 4.163 | 3.649 | 1.855 | 1.105 | — |
| CD8+ | 1.603 | 1.506 | 0.281 | 0.226 | — |
| IgM+IgD+ | 1.077 | 0.646 | 0.959 | 0.434 | — |
Data shown are the averages (means and SD) of the absolute sizes of the cell populations carrying indicated surface markers in single-cell suspensions of bone marrow, spleen, and lymph nodes of 2-month-old control and RhoH-null mice. n [control]/[RhoH−/−]: 5/5.
— indicates not significant (P > .05).