Tumor-suppressor genes epigenetically inactivated in other cancers that were up-regulated by Bmi-1 knockdown in L428 cells
| Gene symbol . | Gene ID . | Fold change after Bmi-1 knockdown . | Gene title/description . |
|---|---|---|---|
| DLC1 | NM024767 | 2.0 | Deleted in liver cancer 1 |
| ATM | BG623786 | 2.3 | Ataxia telangiectasia mutated gene |
| CASP8 | A1830471 | 2.5 | Caspase 8, apoptosis-related cysteine peptidase |
| ID4 | U16153 | 2.4 | Inhibitor of DNA-binding 4, dominant-negative helix-loop-helix protein |
| IGSF4 | AU146373 | 4.6 | Immunoglobulin superfamily, member 4/TSLC1 |
| TUSC3 | A1760262 | 4.6 | Tumor-suppressor candidate 3 |
| GLIPR1 | AK024153 | 5.2 | GLI pathogenesis related-1 |
| FAM45A | AK025354 | 6.06 | Family with sequence similarity 45, member A |
| SERPINB5 | NM002639 | 7.5 | Serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| LOX | BE503425 | 21.1 | Lysyl oxidase |
| ST18 | BC025662 | 29.8 | Suppression of tumorigenicity 18 |
| MEG3 | BC036602 | 36.7 | Maternally expressed 3 |
| Gene symbol . | Gene ID . | Fold change after Bmi-1 knockdown . | Gene title/description . |
|---|---|---|---|
| DLC1 | NM024767 | 2.0 | Deleted in liver cancer 1 |
| ATM | BG623786 | 2.3 | Ataxia telangiectasia mutated gene |
| CASP8 | A1830471 | 2.5 | Caspase 8, apoptosis-related cysteine peptidase |
| ID4 | U16153 | 2.4 | Inhibitor of DNA-binding 4, dominant-negative helix-loop-helix protein |
| IGSF4 | AU146373 | 4.6 | Immunoglobulin superfamily, member 4/TSLC1 |
| TUSC3 | A1760262 | 4.6 | Tumor-suppressor candidate 3 |
| GLIPR1 | AK024153 | 5.2 | GLI pathogenesis related-1 |
| FAM45A | AK025354 | 6.06 | Family with sequence similarity 45, member A |
| SERPINB5 | NM002639 | 7.5 | Serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| LOX | BE503425 | 21.1 | Lysyl oxidase |
| ST18 | BC025662 | 29.8 | Suppression of tumorigenicity 18 |
| MEG3 | BC036602 | 36.7 | Maternally expressed 3 |