Apoptosis- and cell-cycle-related genes differentially regulated by MRP8/MRP14 in HMECs
| Gene . | Gene symbol . |
|---|---|
| Genes up-regulated by MRP8/MRP14 | |
| Bak (Bcl-2—antagonist/killer 1) | BAK1 |
| Bax (Bcl-2—associated X protein) | BAX |
| Transcription factor p53 | TP53 |
| Genes down-regulated by MRP8/MRP14 | |
| ERCC5 (excision repair protein complementation group 5) | ERCC5 |
| NIMA (never in mitosis gene A)–related kinase 3 | NEK3 |
| MAD2 (mitotic arrest deficient 2)–like 1 | MAD2L1 |
| Cell division cycle 2 (G1 to S and G2 to M) | CDC2 |
| Apoptosis inhibitor 5 | API5 |
| NIMA-related kinase 4 | NEK4 |
| Stromal antigen 2 | STAG2 |
| c-FLIP (CASP8 and FADD-like apoptosis regulator) | CFLAR |
| Cell growth regulator with ring finger domain 1 | CGRRF1 |
| Beta-amyloid binding protein | BBP |
| Postmeiotic segregation increased 1 | PMS1 |
| Calpastatin | CAST |
| Retinoblastoma 1 | RB1 |
| Gene . | Gene symbol . |
|---|---|
| Genes up-regulated by MRP8/MRP14 | |
| Bak (Bcl-2—antagonist/killer 1) | BAK1 |
| Bax (Bcl-2—associated X protein) | BAX |
| Transcription factor p53 | TP53 |
| Genes down-regulated by MRP8/MRP14 | |
| ERCC5 (excision repair protein complementation group 5) | ERCC5 |
| NIMA (never in mitosis gene A)–related kinase 3 | NEK3 |
| MAD2 (mitotic arrest deficient 2)–like 1 | MAD2L1 |
| Cell division cycle 2 (G1 to S and G2 to M) | CDC2 |
| Apoptosis inhibitor 5 | API5 |
| NIMA-related kinase 4 | NEK4 |
| Stromal antigen 2 | STAG2 |
| c-FLIP (CASP8 and FADD-like apoptosis regulator) | CFLAR |
| Cell growth regulator with ring finger domain 1 | CGRRF1 |
| Beta-amyloid binding protein | BBP |
| Postmeiotic segregation increased 1 | PMS1 |
| Calpastatin | CAST |
| Retinoblastoma 1 | RB1 |