Phenotype of 5 tonsillar B-cell subpopulations
| Marker . | Population . | ||||
|---|---|---|---|---|---|
| Naive . | Pro-GC . | Pre-GC . | GC . | Memory . | |
| CD5 | − | −/+ | − | +/− | −/+ |
| CD10 | − | − | + | + | − |
| CD19 | + | + | + | + | + |
| CD20 | + | + | + | ++ | ++ |
| CD21 | +/− | + | −/+ | + | + |
| CD23 | −/+ | − | |||
| CD27 | − | − | − | − | + |
| CD38 | − | − | + | + | − |
| CD39 | − | +/− | − | − | −/+ |
| CD40 | + | ++ | + | + | + |
| CD44 | + | + | + | + | + |
| CD69 | −/+ | − | − | − | |
| CD71 | − | + | + | + | |
| CD77 | − | −/+ | +/− | ++/− | −/+ |
| CD80 | + | +++ | ++ | ++ | + |
| CD86 | + | ++ | +++ | ++ | + |
| CD95 | − | + | + | + | − |
| HLA-DR | + | + | + | ++ | + |
| IgD | + | + | + | − | − |
| IgM | −/+ | −/+ | −/+ | − | − |
| Marker . | Population . | ||||
|---|---|---|---|---|---|
| Naive . | Pro-GC . | Pre-GC . | GC . | Memory . | |
| CD5 | − | −/+ | − | +/− | −/+ |
| CD10 | − | − | + | + | − |
| CD19 | + | + | + | + | + |
| CD20 | + | + | + | ++ | ++ |
| CD21 | +/− | + | −/+ | + | + |
| CD23 | −/+ | − | |||
| CD27 | − | − | − | − | + |
| CD38 | − | − | + | + | − |
| CD39 | − | +/− | − | − | −/+ |
| CD40 | + | ++ | + | + | + |
| CD44 | + | + | + | + | + |
| CD69 | −/+ | − | − | − | |
| CD71 | − | + | + | + | |
| CD77 | − | −/+ | +/− | ++/− | −/+ |
| CD80 | + | +++ | ++ | ++ | + |
| CD86 | + | ++ | +++ | ++ | + |
| CD95 | − | + | + | + | − |
| HLA-DR | + | + | + | ++ | + |
| IgD | + | + | + | − | − |
| IgM | −/+ | −/+ | −/+ | − | − |
Relative MFIs of different levels are indicated by multiple + signs. The order of + or − signs indicates predominant population.