List of genes comprising the 70-gene high-risk signature
| Rank . | Chromosome . | Affymetrix probe set . | Gene symbol . |
|---|---|---|---|
| Q4 | |||
| 1 | 8q21.13 | 202345_s_at | FABP5 |
| 2 | Xp22.12 | 1555864_s_at | PDHA1 |
| 3 | 5p15.33 | 204033_at | TRIP13 |
| 4 | 1q22 | 206513_at | AIM2 |
| 5 | 2p24.1 | 1555274_a_at | SELI |
| 6 | 21q22.3 | 211576_s_at | SLCI19A1 |
| 7 | 3p21.3 | 204016_at | LARS2 |
| 8 | 1q43 | 1565951_s_at | OPN3 |
| 9 | 1q31.3 | 219918_s_at | ASPM |
| 10 | 12q15 | 201947_s_at | CCT2 |
| 11 | 16p13.3 | 213535_s_at | UBE2I |
| 12 | 20q13.31 | 204092_s_at | STK6 |
| 13 | 1p36.33 | 213607_x_at | FLJ13052 |
| 14 | Xq12 | 208117_s_at | LAS1L |
| 15 | 17q25 | 210334_x_at | BIRC5 |
| 16 | 3q27 | 204023_at | RFC4 |
| 17 | 1q21.2 | 201897_s_at | CKS1B |
| 18 | 19q13.12 | 216194_s_at | CKAP1 |
| 19 | 1p11 | 225834_at | MGC57827 |
| 20 | 19q13.12 | 238952_x_at | DKFZp779O175 |
| 21 | 17p13.3 | 200634_at | PFN1 |
| 22 | 19p13.2 | 208931_s_at | ILF3 |
| 23 | 1q22 | 206332_s_at | IFI16 |
| 24 | 7p13 | 220789_s_at | TBRG4 |
| 25 | 10p11.23 | 218947_s_at | PAPD1 |
| 26 | 8q24 | 213310_at | EIF2C2 |
| 27 | 3q12.1 | 224523_s_at | MGC4308 |
| 28 | 1p36.13 | 201231_s_at | ENO1 |
| 29 | 18q12.1 | 217901_at | DSG2 |
| 30 | 6q22 | 226936_at | C6orf173 |
| 31 | 8q24.3 | 58696_at | EXOSC4 |
| 32 | 1q23.3 | 200916_at | TAGLN2 |
| 33 | 3q21 | 201614_s_at | RUVBL1 |
| 34 | 16p11.2 | 200966_x_at | ALDOA |
| 35 | 2p25.1 | 225082_at | CPSF3 |
| 36 | 1q43 | 242488_at | NA |
| 37 | 3q12.3 | 243011_at | MGC15606 |
| 38 | 22q13.1 | 201105_at | LGALS1 |
| 39 | 3p25.3 | 224200_s_at | RAD18 |
| 40 | 20p11 | 222417_s_at | SNX5 |
| 41 | 1q21.2 | 210460_s_at | PSMD4 |
| 42 | 12q24.3 | 200750_s_at | RAN |
| 43 | 1q32.1 | 206364_at | KIF14 |
| 44 | 7p15.2 | 201091_s_at | CBX3 |
| 45 | 12q22 | 203432_at | TMPO |
| 46 | 17q24.2 | 221970_s_at | DKFZP586L0724 |
| 47 | 11p15.4 | 212533_at | WEE1 |
| 48 | 3p12 | 213194_at | ROBO1 |
| 49 | 5q33.1 | 244686_at | TCOF1 |
| 50 | 8q23.1 | 200638_s_at | YWHAZ |
| 51 | 10q23.31 | 205235_s_at | MPHOSPH1 |
| Q1 | |||
| 1 | 9q31.3 | 201921_at | GNG10 |
| 2 | 1p13 | 227278_at | NA |
| 3 | Xp22.3 | 209740_s_at | PNPLA4 |
| 4 | 20q11.21 | 227547_at | NA |
| 5 | 10q25.1 | 225582_at | KIAA1754 |
| 6 | 1p13.2 | 200850_s_at | AHCYL1 |
| 7 | 1p13.3 | 213628_at | MCLC |
| 8 | 1p22 | 209717_at | EVI5 |
| 9 | 1p13.3 | 222495_at | AD-020 |
| 10 | 6p21.31 | 1557277_a_at | NA |
| 11 | 1p22.1 | 1554736_at | PARG1 |
| 12 | 1p22 | 218924_s_at | CTBS |
| 13 | 9p13.2 | 226954_at | UBE2R2 |
| 14 | 1p34 | 202838_at | FUCA1 |
| 15 | 13q14 | 230192_at | RFP2 |
| 16 | 12q13.11 | 48106_at | FLJ20489 |
| 17 | 11q13.1 | 237964_at | NA |
| 18 | 2p22.3 | 202729_s_at | LTBP1 |
| 19 | 1p13.1 | 212435_at | TRIM33 |
| Rank . | Chromosome . | Affymetrix probe set . | Gene symbol . |
|---|---|---|---|
| Q4 | |||
| 1 | 8q21.13 | 202345_s_at | FABP5 |
| 2 | Xp22.12 | 1555864_s_at | PDHA1 |
| 3 | 5p15.33 | 204033_at | TRIP13 |
| 4 | 1q22 | 206513_at | AIM2 |
| 5 | 2p24.1 | 1555274_a_at | SELI |
| 6 | 21q22.3 | 211576_s_at | SLCI19A1 |
| 7 | 3p21.3 | 204016_at | LARS2 |
| 8 | 1q43 | 1565951_s_at | OPN3 |
| 9 | 1q31.3 | 219918_s_at | ASPM |
| 10 | 12q15 | 201947_s_at | CCT2 |
| 11 | 16p13.3 | 213535_s_at | UBE2I |
| 12 | 20q13.31 | 204092_s_at | STK6 |
| 13 | 1p36.33 | 213607_x_at | FLJ13052 |
| 14 | Xq12 | 208117_s_at | LAS1L |
| 15 | 17q25 | 210334_x_at | BIRC5 |
| 16 | 3q27 | 204023_at | RFC4 |
| 17 | 1q21.2 | 201897_s_at | CKS1B |
| 18 | 19q13.12 | 216194_s_at | CKAP1 |
| 19 | 1p11 | 225834_at | MGC57827 |
| 20 | 19q13.12 | 238952_x_at | DKFZp779O175 |
| 21 | 17p13.3 | 200634_at | PFN1 |
| 22 | 19p13.2 | 208931_s_at | ILF3 |
| 23 | 1q22 | 206332_s_at | IFI16 |
| 24 | 7p13 | 220789_s_at | TBRG4 |
| 25 | 10p11.23 | 218947_s_at | PAPD1 |
| 26 | 8q24 | 213310_at | EIF2C2 |
| 27 | 3q12.1 | 224523_s_at | MGC4308 |
| 28 | 1p36.13 | 201231_s_at | ENO1 |
| 29 | 18q12.1 | 217901_at | DSG2 |
| 30 | 6q22 | 226936_at | C6orf173 |
| 31 | 8q24.3 | 58696_at | EXOSC4 |
| 32 | 1q23.3 | 200916_at | TAGLN2 |
| 33 | 3q21 | 201614_s_at | RUVBL1 |
| 34 | 16p11.2 | 200966_x_at | ALDOA |
| 35 | 2p25.1 | 225082_at | CPSF3 |
| 36 | 1q43 | 242488_at | NA |
| 37 | 3q12.3 | 243011_at | MGC15606 |
| 38 | 22q13.1 | 201105_at | LGALS1 |
| 39 | 3p25.3 | 224200_s_at | RAD18 |
| 40 | 20p11 | 222417_s_at | SNX5 |
| 41 | 1q21.2 | 210460_s_at | PSMD4 |
| 42 | 12q24.3 | 200750_s_at | RAN |
| 43 | 1q32.1 | 206364_at | KIF14 |
| 44 | 7p15.2 | 201091_s_at | CBX3 |
| 45 | 12q22 | 203432_at | TMPO |
| 46 | 17q24.2 | 221970_s_at | DKFZP586L0724 |
| 47 | 11p15.4 | 212533_at | WEE1 |
| 48 | 3p12 | 213194_at | ROBO1 |
| 49 | 5q33.1 | 244686_at | TCOF1 |
| 50 | 8q23.1 | 200638_s_at | YWHAZ |
| 51 | 10q23.31 | 205235_s_at | MPHOSPH1 |
| Q1 | |||
| 1 | 9q31.3 | 201921_at | GNG10 |
| 2 | 1p13 | 227278_at | NA |
| 3 | Xp22.3 | 209740_s_at | PNPLA4 |
| 4 | 20q11.21 | 227547_at | NA |
| 5 | 10q25.1 | 225582_at | KIAA1754 |
| 6 | 1p13.2 | 200850_s_at | AHCYL1 |
| 7 | 1p13.3 | 213628_at | MCLC |
| 8 | 1p22 | 209717_at | EVI5 |
| 9 | 1p13.3 | 222495_at | AD-020 |
| 10 | 6p21.31 | 1557277_a_at | NA |
| 11 | 1p22.1 | 1554736_at | PARG1 |
| 12 | 1p22 | 218924_s_at | CTBS |
| 13 | 9p13.2 | 226954_at | UBE2R2 |
| 14 | 1p34 | 202838_at | FUCA1 |
| 15 | 13q14 | 230192_at | RFP2 |
| 16 | 12q13.11 | 48106_at | FLJ20489 |
| 17 | 11q13.1 | 237964_at | NA |
| 18 | 2p22.3 | 202729_s_at | LTBP1 |
| 19 | 1p13.1 | 212435_at | TRIM33 |