Table 1 Association of parameters with... | American Society of Hematology

Table 1

Association of parameters with response among all patients and among those who survived beyond day 28 of therapy initiation

	All nonresponders		Nonresponders surviving beyond day 28*		Responders†		P‡
	n	Mean (95% CIs)	n	Mean (95% CIs)	n	Mean (95% CIs)	P‡
CD33 expression	197	54.8 (48.6-61.0)	172	53.9 (47.2-60.7)	69	71.2 (57.2-85.2)	.04; .03
Pgp efflux	170	1.84 (1.73-1.96)	148	1.86 (1.74-1.99)	60	1.44 (1.31-1.57)	<.001; <.001
CD33 expression-blast % ratio	197	1.52 (1.26-1.78)	172	1.56 (1.27-1.85)	69	3.31 (2.11-4.53)	.005; .006
% AML blasts	197	55.9 (51.8-60.0)	172	54.7 (50.3-59.2)	69	44.7 (37.7-51.8)	.008; .02

	All nonresponders		Nonresponders surviving beyond day 28*		Responders†		P‡
	n	Mean (95% CIs)	n	Mean (95% CIs)	n	Mean (95% CIs)	P‡
CD33 expression	197	54.8 (48.6-61.0)	172	53.9 (47.2-60.7)	69	71.2 (57.2-85.2)	.04; .03
Pgp efflux	170	1.84 (1.73-1.96)	148	1.86 (1.74-1.99)	60	1.44 (1.31-1.57)	<.001; <.001
CD33 expression-blast % ratio	197	1.52 (1.26-1.78)	172	1.56 (1.27-1.85)	69	3.31 (2.11-4.53)	.005; .006
% AML blasts	197	55.9 (51.8-60.0)	172	54.7 (50.3-59.2)	69	44.7 (37.7-51.8)	.008; .02

n indicates the number of patients with available data; 95% CIs, 95% confidence intervals.

This group excludes patients who died within 28 days of therapy initiation.

CR + CRp.

First P value among all patients; second value excludes patients who died within 28 days of therapy initiation.