Table 2

Association between asparagine depletion and response

ParameterSample sizeDepletedNondepletedP*Hazard ratio95% CI
CR, % 85 87 73 .113 NA NA 
Median DFS, mo 71 25 12 .010 2.21 1.19-4.13 
Relapse rate, % 85 71 91 .064 NA NA 
Median OS, mo 85 31 13 .001 2.37 1.38-4.09 
ParameterSample sizeDepletedNondepletedP*Hazard ratio95% CI
CR, % 85 87 73 .113 NA NA 
Median DFS, mo 71 25 12 .010 2.21 1.19-4.13 
Relapse rate, % 85 71 91 .064 NA NA 
Median OS, mo 85 31 13 .001 2.37 1.38-4.09 

NA indicates not applicable

*

P values are from the Wilcoxon 2-sample test, chi-square test, or log-rank test, as appropriate.

No patients died in CR.

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