Table 1 Association between baseline... | American Society of Hematology

Table 1

Association between baseline characteristics and asparagine depletion

Parameter	Sample size	Depleted	Nondepleted	P*
No. of patients	85	63	22	—
Median age,† y (range)	85	32 (17-70)	48 (22-71)	.009
Median WBC count, × 10⁹/L (range)	84	7.7 (1.0-393.0)	8.4 (1.0-131.1)	.738
Performance status, median	84	1	1	.674
Immunophenotype	62	—	—	.099
B lineage, no. of patients (%)	50	34 (68)	16 (32)	—
T lineage, no. of patients (%)	12	11 (92)	1 (8)	—
Unfavorable karyotype, no. of patients (%)	85	14 (22)	7 (32)	.369

Parameter	Sample size	Depleted	Nondepleted	P*
No. of patients	85	63	22	—
Median age,† y (range)	85	32 (17-70)	48 (22-71)	.009
Median WBC count, × 10⁹/L (range)	84	7.7 (1.0-393.0)	8.4 (1.0-131.1)	.738
Performance status, median	84	1	1	.674
Immunophenotype	62	—	—	.099
B lineage, no. of patients (%)	50	34 (68)	16 (32)	—
T lineage, no. of patients (%)	12	11 (92)	1 (8)	—
Unfavorable karyotype, no. of patients (%)	85	14 (22)	7 (32)	.369

— indicates not applicable.

P values are from the Wilcoxon 2-sample test, chi-square test, or log-rank test, as appropriate.

Increasing age was associated with decreasing total number of PEG-ASP doses administered (Wilcoxon P = .002).