Table 2

Percentage of the 240 patients falling into the 2 primary genotypic groups at each of 16 loci

LocusGenotype groups% in 1st genotype group% in 2nd genotype group
CYP3A4*1B AA vs AG and GG 79.6 20.4 
CYP3A5*3 AA and AG vs GG 32.1 67.9 
GSTM1 deletion Null vs nonnull 42.5 57.5 
GSTP1 313A>G AA and AG vs GG 82.9 17.1 
GSTT1 deletion Null vs nonnull 15.8 84.2 
MDR1 exon 21 G>T/A GG vs others 36.7 63.3 
MDR1 exon 26 C>T CC and CT vs TT 76.3 23.7 
MTHFR 677C>T CC vs CT and TT 48.8 51.2 
MTHFR 1298A>C AA vs AC and CC 53.8 46.2 
NR3C1 1088A>G AA vs AG 96.7 3.3 
RFC 80A>G AA and AG vs GG 68.3 31.7 
TPMT combined genotypes Others vs 238GG, 460GG, and 719AA 5.8 94.2 
TYMS enhancer repeat 3AND3 vs others 31.7 68.3 
UGT1A1 promoter repeat 7AND7 vs others 10.4 87.9 
VDR Fokl T>C CC vs CT and TT 46.3 53.7 
VDR intron8 G>A AA and AG vs GG 54.2 45.8 
LocusGenotype groups% in 1st genotype group% in 2nd genotype group
CYP3A4*1B AA vs AG and GG 79.6 20.4 
CYP3A5*3 AA and AG vs GG 32.1 67.9 
GSTM1 deletion Null vs nonnull 42.5 57.5 
GSTP1 313A>G AA and AG vs GG 82.9 17.1 
GSTT1 deletion Null vs nonnull 15.8 84.2 
MDR1 exon 21 G>T/A GG vs others 36.7 63.3 
MDR1 exon 26 C>T CC and CT vs TT 76.3 23.7 
MTHFR 677C>T CC vs CT and TT 48.8 51.2 
MTHFR 1298A>C AA vs AC and CC 53.8 46.2 
NR3C1 1088A>G AA vs AG 96.7 3.3 
RFC 80A>G AA and AG vs GG 68.3 31.7 
TPMT combined genotypes Others vs 238GG, 460GG, and 719AA 5.8 94.2 
TYMS enhancer repeat 3AND3 vs others 31.7 68.3 
UGT1A1 promoter repeat 7AND7 vs others 10.4 87.9 
VDR Fokl T>C CC vs CT and TT 46.3 53.7 
VDR intron8 G>A AA and AG vs GG 54.2 45.8 
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